+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Current status of proximal gastric vagotomy

, : Current status of proximal gastric vagotomy. Annals of Surgery 209(2): 131-148

Proximal gastric vagotomy is nearing its twentieth year in clinical use as an operation for peptic ulcer disease. No other acid-reducing operation has undergone as much scrutiny or study. At this time, the evidence of such studies and long-term follow-up strongly supports the use of proximal gastric vagotomy as the treatment of choice for chronic duodenal ulcer in patients who have failed medical therapy. Its application in treating the complications of peptic ulcer disease, which recently have come to represent an increasingly greater percentage of all operations done for peptic ulcer disease, is well-tested. However, initial series suggest that it should probably occupy a prominent role in treating some of these complications, particularly in selected patients, in the future. The operation has the well-documented ability to reduce gastric acid production, not inhibit gastric bicarbonate production, and also minimally inhibit gastric motility. The combination of these physiologic results after proximal gastric vagotomy, along with preservation of the normal antropyloroduodenal mechanism of gastrointestinal control, serve to allow patients with proximal gastric vagotomy the improved benefits of significantly fewer severe gastrointestinal side effects than are seen after other operations for peptic ulcer disease.


PMID: 2644897

DOI: 10.1097/00000658-198902000-00001

Other references

Somorjai, G.; Kulcsar, M.; Huszenicza, G.; Pethes, G., 1984: Interrelation of milk progesterone and plasma beta -carotene concentrations in the cow. Feeding 113 cows synthetic beta -carotene during winter and early spring, i.e. from 15-20 days pre-partum to 60-80 days post partum, significantly increased both serum beta -carotene concn., and milk progesterone concn. during the luteal phase (5....

Paterson-Brown, S., 1998: Should doctors perform an elective caesarean section on request? Yes, as long as the woman is fully informed. Bmj 317(7156): 462-463

Braun, U.; Eicher, R.; Bracher, V., 1988: Internal reflux in cattle--studies of the abomasal reflux syndrome in various diseases of the digestive system. Schweizer Archiv für Tierheilkunde 130(5): 225-236

Peeters G.; Sieben G.; Symoens J.; Wellens D., 1986: Long term treatment of essential hypertension with ketanserin a new serotonin 2 antagonist alone and in combination with other antihypertensive agents an open multicenter study in outpatients. Angiology 37(10): 774

Lo, Y.M.D.; Noakes, L.; Bowell, P.J.; Fleming, K.A.; Wainscoat, J.S., 1994: Detection of fetal RhD sequence from peripheral blood of sensitized RhD-negative pregnant women. A sensitive PCR-based assay was developed to amplify fetal-derived rhesus D (RhD) sequence from peripheral blood of RhD-negative pregnant women with circulating anti-D. RhD-PCR positivity was detected in 7/22 samples from women bearing RhD-positiv...

Mohrman, D.E., 1982: Lack of influence of potassium or osmolality on steady-state exercise hyperemia. Hyperkalemia, hyperosmolality, and hypoxia are known to have synergistic vasodilatory effects on resting skeletal muscle. The purpose of this study was to determine the importance of hyperkalemia and hyperosmolality in the hyperemia accompanying s...

Albrecht, P.J.; Dahl, J.P.; Stoltzfus, O.K.; Levenson, R.; Levison, S.W., 2002: Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival. At focal CNS injury sites, several cytokines accumulate, including ciliary neurotrophic factor (CNTF) and interleukin-1beta (IL-1beta). Additionally, the CNTF alpha receptor is induced on astrocytes, establishing an autocrine/paracrine loop. How a...

Rooks, B., 2004: M&A in healthcare IT. The deals are smaller but the pace is accelerating. Healthcare Informatics 21(6): 73-74

Wright H.E.Jr, 1981: Vegetation east of the rocky mountains usa 18000 years ago. The various lobes and segments of the southern periphery of the Laurentide ice sheet reached their maximum extension at different times between 21,000 and 14,000 yr ago, but the CLIMAP date of 18,000 yr ago is taken as a reference level to review...

Subba-Rao, G.; Kumari, G., 1983: Some interesting plants common to western Ghats and Eastern Ghats. Bulletin of the Botanical Survey of Indiaub 1983) 23(1-2): 30-37