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Differential regulation of two glutathione-S-conjugate transporters mrp1 and mrp2 during the initial phase of cell proliferation in hepatocytes


, : Differential regulation of two glutathione-S-conjugate transporters mrp1 and mrp2 during the initial phase of cell proliferation in hepatocytes. Hepatology 24(4 PART 2): 258A


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Teo, M.C.C.; Soo, K.Chee., 2013: Cancer trends and incidences in Singapore. Cancer is the leading cause of mortality in Singapore. The age-standardized incidence rates continue to increase as the population grows and ages, and the influence of environmental and lifestyle choices bear their consequences. The increase is mo...

Hardy, K.D.; Wahlin, M.D.; Papageorgiou, I.; Unadkat, J.D.; Rettie, A.E.; Nelson, S.D., 2014: Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells. Idiosyncratic hepatotoxicity has been associated with the oral tyrosine kinase inhibitor lapatinib, which is used in metastatic breast cancer therapy. Lapatinib is extensively metabolized by cytochrome P450 3A4/5 to yield an O-debenzylated metabol...

Xiao, K-Jun.; Wang, W-Xia.; Dai, J-Li.; Zhu, L., 2014: Anti-inflammatory activity and chemical composition of the essential oils from Senecio flammeus. Many species from Senecio genus have been used in traditional medicine, and their pharmacological activities have been demonstrated. This study investigated the chemical composition and anti-inflammatory activities of essential oils from Senecio f...

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Rak, B.; Garbicz, F.; Paskal, W.; Pełka, K.; Marczewska, J.Maja.; Wołosz, D.; Włodarski, Pł., 2016: The expression of MMP-14 and microRNA-410 in FFPE tissues of human endometrial adenocarcinoma. Endometrial cancer (EC) is the most common gynecological malignancy in Europe and North America. It is classified into two types exhibiting different characteristics and prognosis. Type I is an estrogen-dependent tumor, histologically classified a...

Kleven, S.H.; Fan, H.H.; Turner, K.S., 1998: Pen trial studies on the use of live vaccines to displace virulent Mycoplasma gallisepticum in chickens. Groups of 10 8-wk-old chickens that had been vaccinated 4 wk previously with the F strain, ts-11, or 6/85 strain of Mycoplasma gallisepticum (MG) were challenged by placing them in contact with 20 chickens that had been previously infected with th...

Syazarina Sharis, O.; Zulkifli, M.Zainuddin.; Hamzaini, A.Hamid., 2013: Predicting outcome of trial of voiding without catheter in acute urinary retention with intravesical prostatic protrusion. Acute urinary retention (AUR) is one of the most serious complications of benign prostatic hypertrophy. This study was done to predict the outcome of trial of voiding without catheter (TWOC) in patients with AUR with intravesical prostatic protrus...