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Effect of acute bilateral adrenalectomy and reserpine on gastric mucus secretion and mucosal injury in pyloric ligated rats


, : Effect of acute bilateral adrenalectomy and reserpine on gastric mucus secretion and mucosal injury in pyloric ligated rats. African Journal Of Biotechnology: 17, 3143-3148

Adrenalectomy produces many changes in gastric functional parameters including gastric acid secretion, gastric motility and mucosal blood flow. The present study was undertaken to assess the effect of acute bilateral adrenalectomy and reserpine on gastric mucus secretion and degradation in the pyloric ligated rats. Groups of Wistar rats of mixed sexes were adrenalectomized or administered with 5 mg/kg reserpine intraperitoneally or given both treatment followed by pyloric ligation.

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