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Elastin peptide receptor-directed monocyte chemotactic polysaccharides derived from seaweed sporophyll and from infectious fungus


, : Elastin peptide receptor-directed monocyte chemotactic polysaccharides derived from seaweed sporophyll and from infectious fungus. Microbial Pathogenesis: 5 6, 423-434

We discovered that a seaweed sporophyll-derived polysaccharide of brown alga, <i>Wakame</i> (<i>Undaria pinnatifida</i>) bound to monocytes and attracted them <i>in vitro</i> and <i>in vivo</i>. Physicochemical properties, affinity to a lectin-bead column and sugar composition of the chemotactic polysaccharide indicated this molecule to be a highly sulfated fucogalactan.

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