+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Endometrial carcinoma in young women. A report of four cases

, : Endometrial carcinoma in young women. A report of four cases. Journal of Reproductive Medicine 34(10): 845-849

Endometrial carcinoma in young women is a rare but well-documented clinicopathologic entity. Four cases revealed some unusual clinical and pathologic features. Patient 1 was the first recorded case of a young woman (aged 24) on maintenance peritoneal dialysis for chronic renal failure who developed endometrial carcinoma with nonvirilizing oligoovulatory polycystic ovarian enlargement. Following subtotal proctocolectomy for familial polyposis coli complicated by a colonic and rectal carcinoma, patient 2 developed, at age 24, a grade 3 endometrial carcinoma in the absence of any risk factors; she was still alive three years postoperatively despite the subsequent development of a grade 3 astrocytoma in the left temporal region. Patient 3 presented at age 32 after ten years of amenorrhea with the clinical features of the Stein-Leventhal syndrome and abnormal uterine bleeding related to a grade 1 endometrial carcinoma; she also had focal dysplasia and adenocarcinoma in situ of the endocervix. Patient 4, who had no risk factors, developed a grade 2 endometrial carcinoma at age 34 despite constant use of combined oral contraceptives for one year and intermittent exposure to them for the previous ten years. Endometrial carcinoma is a rare but important cause of abnormal uterine bleeding in young women; the prognosis can be improved only by prompt diagnosis and appropriate therapy.


PMID: 2795570

Other references

Chen, J.; Rood, J.I.; McClane, B.A., 2015: Correction for Chen et al., Epsilon-Toxin Production by Clostridium perfringens Type D Strain CN3718 Is Dependent upon the agr Operon but Not the VirS/VirR Two-Component Regulatory System. Mbio 6(1): -

Abul-Hajj, Y.J., 1983: Studies on the mechanism of action of the aromatase inhibitor, 4-hydroxyandrostenedione. [1 beta-3H], [1 alpha,2 alpha-3H] and [1 beta,2 beta-3H] 4-Hydroxyandrostenedione (4-OH-A) were synthesized to study the mechanism of inhibition of aromatase by 4-OH-A. Incubations of [1 beta-3H] and [1 beta,2 beta-3H] 4-OH-A with placental micros...

Muller, R.; Boke, K.; Martin-Neuman, U.; Hanke, W., 1973: Salzwasseradaption und Stottwechsel bei Fischen. Fortschritte Zool, 222-3: 456-467

Taylor Y.S.M.; Young V.R.; Murray E.; Scrimshaw N.S., 1973: Influence of composition and distribution of meals on nitrogen utilization in young men. Federation Proceedings 32(3 PART 1): 916

Bosshardt, S.C.; Benson, R.F.; Fields, B.S., 1997: Flagella are a positive predictor for virulence in Legionella. Pathogenesis of Legionnaires>> disease is strictly related to the ability of the legionellae to infect phagocytic cells, yet surface markers of virulence in Legionella isolates are currently unknown. Rabbit antibodies raised against purified...

Auld, S.C.; Click, E.S.; Heilig, C.M.; Miramontes, R.; Cain, K.P.; Bisson, G.P.; Mac Kenzie, W.R., 2014: Association between tuberculin skin test result and clinical presentation of tuberculosis disease. The tuberculin skin test (TST) is used to test for latent tuberculosis (TB) infection and support the diagnosis of active TB. However, little is known about the relationship between the TST result and the clinical presentation of TB disease. We an...

Wriedt, S.; Jaklin, J.; Al-Nawas, B.; Wehrbein, H., 2012: Impacted upper canines: examination and treatment proposal based on 3D versus 2D diagnosis. The purpose of this diagnostic cross-over study was to evaluate whether three-dimensional (3D) diagnostics (cone-beam computed tomography, CBCT) was superior to two-dimensional (2D) diagnostics (panoramic X-ray, OPG) in patients with impacted uppe...

Duffy, P.; Murphy, P., 1988: The communications predicament in Canadian forestry. Forestry chronicle 64(2): 141-145

Gilboa Garber, N.; Mymon, H.; Oren, A., 1997: Archaeal surface glycoconjugate analysis by lectins. FASEB Journal 11(9): A1244

Kahn L.L.; Simon R.H.; Ryan U.S.; Varani J.; Morganroth M.L., 1990: Hypoxia reoxygenation does not injure endothelial cells or affect pmn adherence. American Review of Respiratory Disease 141(4 PART 2): A161