+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Establishing the diagnosis of Libman-Sacks endocarditis in systemic lupus erythematosus

, : Establishing the diagnosis of Libman-Sacks endocarditis in systemic lupus erythematosus. Journal of General Internal Medicine 23(6): 883-886

CASE: A 43-year-old female with systemic lupus erythematosus (SLE) was admitted with fever and shortness of breath 1 month after aortic valve replacement. A diagnostic workup including chemistries, complete blood count, blood cultures, chest x-ray, and 2-D echocardiogram was performed to determine the etiology of her symptoms and differentiate between acute bacterial endocarditis and Libman-Sacks endocarditis.DISCUSSION: By utilizing Duke's criteria, antiphospholipid antibodies, and serial echocardiography, we were able to make a diagnosis of Libman-Sacks endocarditis. The patient was successfully treated for Libman-Sacks endocarditis and recovered uneventfully.CONCLUSION: This case highlights the challenges of making the correct diagnosis when 2 disease processes present with similar findings.


PMID: 18421506

DOI: 10.1007/s11606-008-0627-8

Other references

Kulenkampff, C., 1970: Chronic patient as a burden in social environment. Deutsches Medizinisches Journal 21(23): 1446-8 Passim

Hammoudeh, Z.S., 2014: Collagenase Clostridium histolyticum injection for plantar fibromatosis (Ledderhose disease). Plastic and Reconstructive Surgery 134(3): 497e-498e

Stevens, C., 1987: Why the feds let an HMO pluck them clean. Medical Economics 64(21): 112-6, 121, 125 Passim

Cepeda, J.A.; Hayman, S.J.; Wilson, A.P.R.; Kibbler, C., 2002: In vitro susceptibility of Gram-positive cocci to linezolid and teicoplanin Use of linezolid for Gram-positive infections in ICU. International Journal of Antimicrobial Agents 19(Supplement 1): S33

Liu, W.; Devaux, Jérôme.J., 2014: Calmodulin orchestrates the heteromeric assembly and the trafficking of KCNQ2/3 (Kv7.2/3) channels in neurons. Mutations in KCNQ2 and KCNQ3 genes are responsible for benign familial neonatal seizures and epileptic encephalopathies. Some of these mutations have been shown to alter the binding of calmodulin (CaM) to specific C-terminal motifs of KCNQ subunit...

Schmidt, Dieter, 2003: Der Kupferkopf (Agkistrodon contortrix). Eine Anfaenger schlange? Teil 2. Reptilia D i- i; 8(3): 65-71 Nr 41

Dijkstra, P.U.; de Bont, L.G.; de Leeuw, R.; Stegenga, B.; Boering, G., 1993: Temporomandibular joint osteoarthrosis and temporomandibular joint hypermobility. For studying the relationship between condylar hypermobility of the temporomandibular joint (TMJ) and osteoarthrosis (OA), 13 patients with bilateral condylar hypermobility were evaluated clinically and radiographically, 30 years after non-surgica...

Hanssen-Bauer, A.; Solvang-Garten, K.; Akbari, M.; Otterlei, M., 2012: X-ray repair cross complementing protein 1 in base excision repair. X-ray Repair Cross Complementing protein 1 (XRCC1) acts as a scaffolding protein in the converging base excision repair (BER) and single strand break repair (SSBR) pathways. XRCC1 also interacts with itself and rapidly accumulates at sites of DNA...

Madan, N.; Marshall, C., 1995: The effects of rooting on carbon partitioning in intact and defoliated stolons of Trifolium repens. Journal of Experimental Botany 46(SUPPL ): 52

Ghersetich, I.; Comacchi, C.; Katsambas, A.; Lotti, T.M., 1999: Cellular steps in pathogenesis of cutaneous necrotizing vasculitis. Clinics in Dermatology 17(5): 597-601