geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

GnRH analogues in the treatment of endometriosis


, : GnRH analogues in the treatment of endometriosis. Obstetrics and Gynecology Clinics of North America 16(1): 123-145

Modifications of the native gonadotropin-releasing hormone (GnRH) decapeptide have led to longer-acting compounds with increased binding ability. Pharmacologic doses of agonists result in suppression of ovarian estradiol production to levels similar to oophorectomized patients. The resultant hypoestrogenism is associated with regression in endometrial implant size. Both subjective and objective clinical improvement have been reported. Recent studies document that a reversible state of hypogonadism is effective treatment for endometriosis.

US$29.90

PMID: 2526312


Other references

Hammond, H.Kirk, 2005: Why FRET? Focus on b-Adrenergic and muscarinic receptor-induced changes in cAMP activity in adult cardiac myocytes using a FRET-based biosensor. American Journal of Physiology 289(2): 46-C247

Lopez Galindo A.; Marinoni L.; Ben Aboud A.; Setti M., 1998: Morphology, fabric and chemistry of smectites from Ciros-1, 270 and 274 boreholes, Ross Sea, Antarctica. Boletin Sociedad Espanola de Mineralogia 21: 1-15

Phillips, C.V., 2001: The economics of 'more research is needed'. Background: Results from epidemiology and other health research affect millions of life-years and billions of dollars, and the research directly consumes millions of dollars. Yet we do little to assess the value of research projects for future pol...

Zhang, F.; Xu, H.; Feng, H., 2017: Toward a unified model for predicting color quality of light sources. Considering that the existing color quality (CQ) metrics for light sources cannot correlate well with the subjective evaluation, in an immersive environment equipped with a multichannel LED light source, a psychophysical experiment by categorical...

Kavitharaghavan, Z.; Ragjendran, R.; Vijayaraghavan, C., 2007: Induced systemic resistance to major insect-pests of brinjal through organic farming. Application of organic sources of nutrients and amendments (Farm yard manure, poultry manure, neem cake, mahua cake, pungam cake and biofertilizers i.e. Azospirillum, phosphobacteria and silica solubilizing bacteria) significantly enhanced the pro...

Barke, R.; Gursky, S., 1972: Problems of radiation protection in radiodiagnosis. Radiologia Diagnostica 13(3): 417-425

Hubbard, E.F.; Landwehr, J.M.; Barker, A.R., 1997: Temporal variability in the hydrologic regimes of the United States. Discharge records where flows have not been subject to overt anthropogenic controls have been identified for over 1500 streamflow gauging stations throughout the United States in the US Geological Survey Hydro-Climatic Data Network. These stations...

Loken M.R.; Hayes J.W.; Gohlke J.R.; Brand L., 1972: Nanosecond time resolved proton transfer studies of a naphthol sulfonate serum albumin complex. Federation Proceedings 31(2): 470

Zakrevskiĭ, V.I.; Finn, G.R.; Kharats, K.S., 1976: Polyamines in microorganisms sensitive and resistant to antibiotics. Intracellular contents of polyamine dancyl derivatives were determined by the method of thin-layer chromatography in Coli and typhoid fever bacteria sensitive to antibiotics and their variants resistant to streptomycin, levomycetin, chlortetracyli...

Khattak, M.N.; Matthews, R.C., 1993: A comparison of the DNA fragment patterns of the mouse-virulent challenge strains and clinical isolates of Bordetella pertussis. The DNA fragment patterns of two mouse-virulent strains of Bordetella pertussis, commonly used in animal protection tests, were compared to those of clinical isolates. Strain W.18-323 and six variants were examined together with strain 353/Z and t...