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Initial study on the association of lipoprotein lipase gene polymorphisms with coronary heart disease

, : Initial study on the association of lipoprotein lipase gene polymorphisms with coronary heart disease. Zhonghua Xinxueguanbing Zazhi 26(4): 309-312, Aug

Objective. To explore the association of LPL gene polymorphisms with CHD. Methods. 106 patients in myocardial infarction survivors were analyzed through a case-control study. Results. The conditional logistic regression analysis demonstrated that 5 factors were associated with CHD. The risk factors were smoking, LPL genotype PVU II (- -) and haplotype H+ P-, while high density lipoprotein cholesterol (HDL-C), apolipoprotein A/B (ApoA/B) ratio seemed as protective factors. After controlling the effect of the other variables, OR of LPL genotype PVU II (- -) and haplotype H+ P- were 17.18 and 3.67, while OR of HDL-C, ApoA/B ratio were respectively 0. 14, 0.15 in model A and 0. 04, 0.09 in model B. Conclusion. These results indicated that LPL genotype PVUII (- -) or haplotype H+ P- other than the conventional risk factors were contributing in CHD and that HDL-C, ApoA/B ratio may be the better independent predictors for CHD than the other plasma lipid parameters.


Other references

Soni, N.; Jain, A.; Kumar, S.; Pandey, C.M.; Awasthi, A., 2016: Arterial spin labeling magnetic resonance perfusion study to evaluate the effects of age and gender on normal cerebral blood flow. Arterial spin labeling (ASL) is a noninvasive magnetic resonance (MR) perfusion technique to detect changes in blood flow. This study was undertaken to obtain a reference set of normal values of cerebral blood flow (CBF) in different age groups us...

Anonymous, 2017: Errors in Figure and Table. JAMA Pediatrics 171(6): 602-602

Kim Y.U.; Park Y.S.; Kim D.S., 1987: Development of eggs larvae and juveniles of loach misgurnus mizolepis gunther. The cyprinid loach, Misgurnus mizolepis Gunther, a freshwater teleost, is a member of the family Cobitidae and is known to distribute in Korea and China. This fish is considered to be an excellent food fish in Korea. This report is a description o...

Bentz, M.; Barth, T.F.E.; Bock, D.; Schlotter, M.; Lichter, P.; Doehner, H.; Moeller, P., 1998: Primary mediastinal B-cell lymphomas are characterized by gains of chromosome arm 9p. Annals of Hematology 77(SUPPL 2): S180

Freedom, R.M.; Yoo, S-Joon.; Perrin, D., 2005: The biological "scrabble" of pulmonary arteriovenous malformations: considerations in the setting of cavopulmonary surgery. Pulmonary arteriovenous fistulas are vascular malformations, which, by virtue of producing abnormal vascular connections proximal to the units of gas exchange, result in intrapulmonary right-to-left shunting. These malformations or fistulas reflec...

Allen, H.; Brewer, L., 1985: A review of current northern spotted owl (Strix occidentalis caurina) research in Washington state. USDA Forest Service general technical report PNW United States Pacific Northwest Forest and Range Experiment Station: (185) 55-57

Kasumov K.M.; Liberman E.A.; Nenashev V.A.; Yurkov I.S., 1975: Study of cation selectivity of bi molecular membranes in the presence of nystatin and amphotericin b. Biofizika 20(1): 62-65

Siegrist, J.; Weber, I., 1983: Status threat in mid-adulthood and its health consequences--medical sociologic findings in coronary diseases. Starting from a socio-physiological approach to the study of stress we define a distinct class of critical experiences called "active distress" which consists of enhanced effort due to external demands and limited success or control over...

MacHarg, M.A.; Becht, J.L., 1983: The pharmacology of heparin prophylaxis. Journal of the American Veterinary Medical Association 183(1): 129-130

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