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Management of congestive heart failure: neuroendocrine approach


, : Management of congestive heart failure: neuroendocrine approach. Israel Journal of Medical Sciences 29(1): 6-10

The term heart failure is a complex of clinical syndromes caused by "neuroendocrine" compensatory responses that are renal, neural, hormonal and hemodynamic in nature. Activation of these multiple systems--as a result of renin, angiotensin II and the action of circulatory catecholamines--causes the release of norepinephrine vasopressin and aldosterone. These responses contribute to the arteriolar constriction and salt and water retention that promote central pooling with an increase in pre- and afterload of the already failing heart, causing deterioration of the congestive heart failure (CHF). Therapy for this clinical syndrome is aimed at reducing both pre- and afterload with vasodilators, which produce a profoundly favorable effect on left ventricular performances. Beta blocking agents, which inhibit the increased sympathetic mediated vasoconstriction, up-regulate beta receptors and thus restore responsiveness to the failing heart. Inotropic agents, such as digitalis and amrinone/milrinone are reserved for patients with dilated failing heart and impaired systolic function; recently a synthetic atrial natriuretic factor has been developed for potential use in CHF. Ultrafiltration is also used in refractory preoperative CHF with cardiac abnormalities. Neuroendocrine responses to CHF are treated today directly by improving central hemodynamic imbalance in these patients.

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PMID: 8454456


Other references

Johnson, R., F.; Gosliner, T., M., 2001: Two new species of Thorunna Bergh 1878 (Mollusca: Nudibranchia: Chromodorididae) from the Indo-Pacific. The genus Thorunna previously included eleven described species. Two new species from the Indo-Pacific tropics, Thorunna kahuna and Thorunna halourga are described. Thorunna kahuna is the only known species in the genus with both large, visible ma...

Heizmann C.W., 1987: Parvalbumin and sarcoplasmic acetylcholinesterase after cross reinnervation of rat muscles. Journal Of Muscle Research & Cell Motility: 56-57

Mccrackin, B.; Bradfield, B., 1986: Tennessee: a better year ahead. Economic review Federal Reserve Bank of Atlanta 71(2): 37-49

H.Guoqi, 1987: On the tectonics of the Paleozoic fold belts in Northern China. Chuan Kuo Kuo Tsao Ti Chih Hsueh Shu Hui I = International Symposium on Tectonic Evolution and Dynamics of Continental Lithosphere 3, Vol

Felice, A., 1989: Stress. Under pressure. Nursing Standard 1987) 3(24): 21-22

Stevenson, W.F., 1898: The EFFECTS of the DUM-DUM BULLET from a SURGICAL POINT of VIEW. British Medical Journal 1(1951): 1324-1325

Annesi, J.J.; Johnson, P.H.; Porter, K.J., 2016: Bi-Directional Relationship Between Self-Regulation and Improved Eating: Temporal Associations With Exercise, Reduced Fatigue, and Weight Loss. Severely obese men and women (body mass index ≥ 35 ≤ 55 kg/m(2); M(age) = 44.8 years, SD = 9.3) were randomly assigned to a 6-month physical activity support treatment paired with either nutrition education (n = 83) or cognitive-behavioral nut...

Protić, A.; Horvat, M.; Komen-Usljebrka, H.; Frkovic, V.; Zuvic-Butorac, M.; Bukal, Kšimir.; Sustic, A., 2011: Benefit of the minimal invasive ultrasound-guided single shot femoro-popliteal block for ankle surgery in comparison with spinal anesthesia. Ultrasound-guided regional anesthesia has gained popularity for ankle and foot surgery. The aim of our study was to investigate the sufficiency of anesthesia for ankle surgery as well as duration of analgesia in postoperative period, using minimal...

Jelliffe, Derrick-Brian, 1979: A Good nutritional start, improving the nutrition of mothers and young children. Recommendations for the improvement of maternal and child nutrition are presented in a report prepared in recognition of the International Year of the Child. Prenatal nutrition and infant feeding have great consequences for subsequent development...

Barnes, P.J., 1991: Preventative therapy in adults with asthma. Respiratory Medicine 85(5): 355-357