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Modification in activity of medullary respiratory-related neurons for vocalization and swallowing


, : Modification in activity of medullary respiratory-related neurons for vocalization and swallowing. Journal of Neurophysiology 71(6): 2294-2304

1. The medullary ventral respiratory group (VRG) in and near the nucleus ambiguus contains neurons related to respiration. Also found here are neurons related to vocalization and swallowing as well as motoneurons of laryngeal, pharyngeal, palatal, and esophageal muscles. Previous reports in anesthetized animals have characterized discharge properties of neurons as they relate to a single behavior, e.g., respiration. Relatively few studies have documented discharge properties during more than one behavior, e.g., respiration and swallowing. Neurons were recorded extracellularly from awake Macaca nemestrina monkeys engaged in a vocalization task. The present paper describes how respiratory-related neurons (RRNs) modify their discharge during vocalization and swallowing. 2. The temporal relation between vocalization, subglottal pressure (SP), and diaphragm electromyogram (EMG) was established from recordings in anesthetized monkeys. Vocalization was elicited by electrical stimulation of the midbrain periaqueductal gray (PAG). Vocalization is preceded by deep inspiration and a brief pause in diaphragm EMG and begins with a rapid increase in positive SP. 3. Extracellularly recorded neural potential from the VRG in three awake monkeys were related to respiration by correlating their discharge with EMGs from the posterior cricoarytenoid or intercostal muscles during quiet respiration. Neurons were classified as inspiratory (INSP; N = 27), phase spanning (PS; N = 20), or expiratory (N = 6) on this basis. 4. A fourth category of cells was defined as a subgroup of INSP cells on the basis of their discharge during vocalization. This group, inspiratory-pause (INSP-PS; N = 10), paused for approximately 100 ms just before vocalization and resumed their activity during vocalization. 5. Of 63 fully analyzed RRNs, 40 (63%) also modulated their activity with vocalization and 3 (5%) with swallowing. Thirteen (21%) RRNs modulated with vocalization, respiration, and swallowing. Seven (11%) cells were modulated only with respiration. 6. Most cells demonstrated a shorter period of activity and a higher discharge rate associated with vocalization in comparison with quiet respiration. Six (30%) of the PS cells demonstrated an augmenting discharge pattern before vocalization, which was different from the other PS cells and different from their pattern during quiet respiration. Thirteen RRNs showed a pause in activity during vocal fold closure associated with swallowing, whereas three cells gave a burst at this time. 7. The higher discharge rate and shorter burst duration preceding vocalization, compared with quiet respiration, may be related to the greater positive SP necessary to support vocalization.(ABSTRACT TRUNCATED AT 400 WORDS)

US$29.90

PMID: 7931518


Other references

Gatfield, I.L.; Stute, R., 1980: Studies on the non-coagulable nitrogenous material present in potato juice. Presence of peptides and glycopeptides. Studies suggest that the noncoagulable nitrogenous material of potato juice, a byproduct of the starch industry, contains peptides and glycopeptides as well as amino acids and amides known to be present. Two polypeptide fractions have mol. wt. in...

Friedman, S.M., 2011: Some effects of diet on the structure of the pancreas. Anatomical Record 94: 461-461

Nasar S.K.T.; Nasar S.A.K., 1979: Induction of controlled de spiralization of chromosomes. CIS (Chromosome Information Service) (26): 3-4

Balmaceda, J.; Asch, R.H.; Fernandez, E.O.; Valenzuela, G.; Eddy, C.A.; Pauerstein, C.J., 1979: Prostaglandin production by rhesus monkey corpora lutea in vitro. Production of prostaglandins (PG) by the corpus luteum was studied during various parts of the luteal phase following spontaneous ovulation in the adult female rhesus monkey. Luteectomy is performed following laparotomy to obtain corpora lutea for...

Mavragani Tsipidou P.; Scouras Z.G.; Haralampidis K.; Lavrentiadou S.; Kastritsis C.D., 1992: The polytene chromosomes of drosophila triauraria and drosophila quadraria sibling species of drosophila auraria. The polytene chromosomes of Drosophila triauraria and D. quadraria, two of the sibling species of D. auraria, were examined. The polytene chromosomes of all three species exhibit very clear homology. Unlike the stock of D. auraria that we studied,...

Buccellato, A.; Cabibbo, L.; L.S.ta, F.; Amuso, M.; Cottone, M.; Pinzello, G.; Traina, M., 1989: The joining of the hepatic ducts at the duodenal papilla. A case report. La Radiologia Medica 78(6): 659-660

Blansett, M.T., 1990: The effects of rewarming hypothermic postanesthesia patients using Thermadrape covering, heat lamps, and warmed cotton blankets. The following article includes a brief review of hypothermia and describes contributing factors that cause hypothermia in the operating room as well as the methods used to rewarm patients in the PACU. Thermadrape coverings (OR Concepts, Inc, Roano...

Grigor'ian, V.A.; Prishliak, V.D., 1977: Nephrotic syndrome caused by thrombosis of the renal veins. Klinicheskaia Meditsina 55(3): 130-131

Wharton, Robert, A., 2006: The species of Sternaulopius Fischer (Hymenoptera : Braconidae, Opiinae) and the Braconid sternaulus. The opiine braconid genus Sternaulopius Fischer is recognized as valid, redefined, and one new species, Sternaulopius duplicatus, from Madagascar, is described. The type species, Sternaulopius bisternaulicus Fischer, is fully redescribed, with ne...

Stewart, J.; Eikelboom, R., 1981: Interaction between effects of stress and morphine on body temperature in rats. Life Sciences 28(9): 1041-1045