geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Octahydronaphthoquinolizines, a new biologically active tetracyclic ring system


, : Octahydronaphthoquinolizines, a new biologically active tetracyclic ring system. Tetrahedron Letters 34(13): 2067-2070

Unsubstituted and methoxy-substituted octahydronaphthoquinolizines, examples of new tetracyclic ring system, have been synthesized in three steps from corresponding 2-tetralones. The various diastereomers of each OHNQ have been separated and characterized by X-ray crystallography and NMR spectroscopy. These compounds have been shown to have activity at selected neurorecepter binding sites.

US$19.90

DOI: 10.1016/s0040-4039(00)60347-7


Other references

Dinsmoor, J.A.; Bowe, C.A.; Green, L.; Hanson, J., 1988: Information on response requirements compared with information on food density as a reinforcer of observing in pigeons. On a variable-interval schedule, pecking the key to the pigeon's right (observing response) produced red or green displays relating to the delivery of grain and its dependence on pecking the key to the left (food key). During various blocks o...

Carvalho, J.L.; Massa, M.V.; Cormier, S.L.; Matsen, M.W.; Dalnoki-Veress, K., 2011: Reversible sphere-to-lamellar wetting transition at the interface of a diblock copolymer system. We use ellipsometry to investigate a transition in the morphology of a sphere-forming diblock copolymer thin-film system. At an interface the diblock morphology may differ from the bulk when the interfacial tension favours wetting of the minority...

Dubois, A., 1988: Some comments on the genus concept in zoology. Monitore Zoologico Italiano, 221: 27-44

Uehara, K.; Ikeda, K.; Hoshihara, A.; Hiyoshi, K.; Fujihashi, H.; Hikima, T.; Miyake, T.; Nakamura, Y., 1980: Periodontal study on the form of plunger ridge. (1). Nihon Shishubyo Gakkai Kaishi 22(4): 643-649

Rindsjö, E.; Hulthén Varli, I.; Ofori, M.F.; Lundquist, M.; Holmlund, U.; Papadogiannakis, N.; Scheynius, A., 2006: Presence of IgE cells in human placenta is independent of malaria infection or chorioamnionitis. We have shown previously that numerous IgE+ macrophage-like cells are present in the villous stroma of full term placenta and that there was no difference in the amount of IgE+ cells between allergic and non-allergic mothers. The presence of such...

Horisberger J D.; Depeursinge F.; Portmann L.; Perret C., 1985: Acute myocardial dysfunction during meningococcal sepsis. A progressive myocardial dysfunction is known to occur in prolonged septic shock. The cases of 2 patients with acute meningococcal infection and Waterhouse-Friderichsen syndrome are reported. Hemodynamic measurements showed, in the early stage, th...

Keinze, H., 1973: Development of biological-dynamic farms in the North Sea coasts climate. Lebendige Erde: 3 149-150

Arakaki, T.; Ichinose, Y.; Yamamoto, K.; Iwanaga, M., 1988: Hemolysin production by Vibrio cholerae non-O1 and O1 El Tor determined by biological and immunological activities. Kansenshogaku Zasshi. Journal of the Japanese Association for Infectious Diseases 62(9): 792-797

Bikhazi A.B., 1984: System approach in the study of butyric acid absorption via rat jejunum. Federation Proceedings: Abstract 4648

Cocks, P.; Powles, R.L.; Chapuis, B.; Alexander, P., 1977: Further evidence of response by leukemia patients in remission to antigen s related to acute myelogenous leukemia. Fifteen patients with acute myelogenous leukemia were studied to determine if their remission blood leukocytes could be stimulated into taking up [3H]thymidine after in vitro culture with their own cryopreserved irradiated AML [acute myelogenous]...