geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Pattern formation in skin development


, : Pattern formation in skin development. International Journal of Developmental Biology 34(1): 33-50

The development of skin and cutaneous appendages in amniote embryos has been submitted to a large number of experimental investigations the results of which have led to a better understanding of the mechanisms whereby this multiform organ arises during embryonic development. In birds, the main appendages are the feathers and the foot scales. Their formation results from a series of inductive events between ectoderm (later epidermis) and subectodermal mesoderm (later individualized dermis). Morphogenetically, the mesodermal (mesenchymal) component of skin is the predominant tissue, insofar as it controls most morphological and physiological features of developing skin and appendages, notably transformation of ectoderm into epidermis, polarization, proliferation and stratification of epidermal cells, initiation, site, size and distribution pattern of epidermal placodes, species-specific architecture of appendages, regional specification of keratin synthesis. The ectodermal (epithelial) component is able to respond to the mesodermal inductive instructions by building feathers and scales in conformity with the specific origin of the dermis. In these epithelial-mesenchymal interactions, extracellular matrix and the microarchitecture of the dermal-epidermal junction appear to play an important role. Indeed extracellular matrix components (primarily collagens, proteoglycans and adhesive glycoproteins) and dermal cell processes close to the epidermal basement membrane become distributed in a microheterogeneous fashion, thus providing a changing substratum for the overlying epidermis. It is assumed that the latter is able to somehow sense the texture and composition of its substratum, and by doing so to appropriately engage in the formation of glabrous, feathered or scaly skin.

US$29.90

PMID: 2203463


Other references

Bialer M.G.; Kahn E.; Libes R.; Krigsman G.; Penchaszadeh V.B., 1986: Complete external feminization and persistent muellerian derivatives in 46 xy infant with the smith lemli opitz syndrome. Pediatric Research 20(4 PART 2): 262A

Anonymous, 2012: Scientists forecast forest carbon loss. For more than 3 years, scientists at the Harvard Forest have scaled towers into the forest canopy and measured the trunks of trees to track how much carbon is stored or lost from the woods each year. This treasure trove of data is part of the nati...

Caurie, M., 1983: Raoults law, water activity and moisture availability in solutions. Journal of food science 48(2): 648-649

Il' in, I.I.; Loskutov, I.A., 1992: Ocular manifestations of Demodex infection. Demodicosis of the eyes was diagnosed by the presence of Demodex at the root of eyelashes in 304 patients treated at the Chelyabinsk Institute, Russia. The infection caused mild chronic symptoms of blepharitis or conjunctivitis in the majority of...

Hatfield, J.G., 1959: Basic principles of surgery. Journal of the American Osteopathic Association 58(6): 353-357

West, S.K.; Rosenthal, F.; Newland, H.S.; Taylor, H.R., 1988: Use of photographic techniques to grade nuclear cataracts. Methods for objectively documenting and grading different varieties of lens opacities are needed in order to conduct research on risk factors for cataracts. This study tested the feasibility and reliability of using two different photographic meth...

Krnjevic, K.; Miledi, R., 1958: Failure of neuromuscular propagation in rats. A study was made of the mechanism of neuromuscular failure during tetanic stimulation in rats, in vitro and in situ. An intracellular electrode may cause failure of propagation along a contracting muscle fiber because of local damage. Repetitive a...

Petrunov, B.; Todorov, D.; Donchev, P., 1977: Sensitization to mites in house dust among children suffering bronchial asthma. The results of studying allergy to domestic dust in 168 patients suffering from bronchial asthma are presented. The diagnosis was made by means of the domestic dust allergen (10000 PNU), fraction E extracted from the whole allergen by Berrens and...

Findlay, H.T.; Andrewes, C.H.; Buckland, F.E., 1966: Francis Edward Buckland, 24 October 1905-2 May 1965. Journal of Pathology and Bacteriology 91(2): 637-640

Solopov, V.N.; Lunichkina, I.V.; Plisko, L.F.; Kolganova, N.A., 1988: Effect of mukodin on indices of mucociliary transport. The authors report some data on the assessment of efficacy of mucodin, a modern expectorant. Its effect on the rate of mucociliary transport, rheological properties of sputum was studied in patients with infectious-allergic bronchial asthma. Admin...