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The lipopolysaccharide of Shigella bacteria as a virulence factor

, : The lipopolysaccharide of Shigella bacteria as a virulence factor. Reviews of Infectious Diseases 13 Suppl 4: S279-S284

The virulence factors of the lipopolysaccharide of Shigella species bacteria include the endotoxic activities of the lipid A component of the molecule and the ability of the polysaccharide chain--the core and the O-antigenic polysaccharide--to provide the bacterium with resistance to host defense mechanisms such as opsonization, phagocytosis, and intracellular killing. Structural features of the lipopolysaccharides of four Shigella species-S. dysenteriae, S. flexneri, S. boydii, and S. sonnei--are described.


PMID: 1710816

DOI: 10.1093/clinids/13.Supplement_4.S279

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