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The organic acids of the blood in the process of death from loss of blood and during the subsequent restoration of the vital functions of the body

, : The organic acids of the blood in the process of death from loss of blood and during the subsequent restoration of the vital functions of the body. Biokhimiia 19(5): 590-598

Dogs were killed by the withdrawal of blood from the femoral artery and then revived by the method of Negovsky. An average of 11.3 meq of organic acids (I) was found in the plasma before the experiment. In most of the experiments the amount of I remained constant, even with the loss of 50% of the blood. With increasing hypoxia the amount of I in the blood (directly proportional to the severity of the hypoxia), began to rise rapidly and was significantly greater than normal at the moment of death. A particularly sharp increase occurred during the initial period of revival. The amount of I only began to decrease after the appearance of independent respiration and approached normal 3 hours after revival. At the time of death, lactic acid accounted for 37% of the total amount of I (normally 20%). At the moment of the appearance of independent respiration, the amount of X-acids (residual I) exceeded the initial value by 85%.


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