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Alarm upon detection of impending sleep state

, : Alarm upon detection of impending sleep state. Official Gazette of the United States Patent & Trademark Office Patents 1265(4), Dec 24

The present invention monitors a physiological process intrinsic to humans and which measures directly the approach of a sleep state. When sleep onset is detected, the subject is restored to a fully awake state by an alert mechanism. Sleep onset is determined by monitoring EEG and EMG signals of the subject with a bispectral index monitor and applying an analysis algorithm to the index values output by the monitor. As a person tires, the value of their bispectral index begins to drop and then oscillate back and forth between two discrete levels. This pattern is consistent among various subjects and indicates an early warning of impending sleep, before a dangerous loss of vigilance has occurred.


Other references

Spaulding, W.D., 1999: State hospitals in the twenty-first century: a formulation. Readers are invited to evaluate the degree to which ideologies are influencing mental health planning and policy development activities in their own system.

Comar, C.L.; Bronner, F., 1969: Mineral metabolism. An advanced treatise. Volume 3. Calcium physiology. My first reaction to the sub-title of this book was to ask what is meant by "An advanced treatise". If it is intended as a warning that few will understand its contents, it is unfair to its writers, and almost any other interpretation th...

Dutta, G.P.; Narain, L.; Shipstone, A.C.; Pandey, V.C.; Mohan Rao, V.K., 1982: Cytochemical, biochemical and electron-microscopic studies of axenic Entamoeba histolytica (strain NIH:200) trophozoites fed with cholesterol. Cholesterol-fed axenic E. histolytica trophozoites showed increased number of food vacuoles with intense acid phosphatase activity in the vacuoles compared with amoebae that were not fed with cholesterol. There was also a marked increase in acid p...

Dunn, E.C.; Small, R.E., 2001: Economics of antihypertensive therapy in the elderly. Because of the high incidence of morbidity and mortality associated with hypertension in the elderly, the treatment of hypertension in this patient group must involve consideration of clinical, humanistic and economic outcomes. The most frequently...

Chen, C.-Yi; Hart, D., J., 1993: A Diels-Alder approach to Stemona alkaloids: Total synthesis of stenine. A total synthesis of dl-stenine (4) is described. Key features involve (1) use of an intramolecular Diels-Alder cycloaddition-aminimide rearrangement sequence to construct the perhydroindole substructure (29 fwdarw 36 fwdarw 27), (2) application o...

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Renaut, W.E., 1906: Occurrence of the Fire-crest at Wimbledon, Surrey. Bulletin of the British Ornithologists' Club, 16 45

Yeh, S.D.; McGary, R.; Benua, R.S., 1978: The subtraction scan for detecting liver involvement in cancer patients. Clinical Bulletin 8(4): 156-160

Solomina, S.N., 1964: Problems of the morphogenesis of silicotuberculosis and silicosis Problems of hygiene, occupational pathology and toxicology. Problems of the morphogenesis of silicotuberculosis and silicosis [Man] Problems of hygiene, occupational pathology and toxicology K voprosam morfogeneza siliko-tuberkuleza i silikoza In: Voprosy gigieny, professional'noi patologii i toksikologii Problems of hygiene, occupational pathology and toxicology 239-247