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Bicyclic-fused pyridines


, : Bicyclic-fused pyridines. Official Gazette of the United States Patent & Trademark Office Patents 1234(3), May 16

Bicyclic-fused pyridines are prepared by introducing the appropriate side chain by reaction of the corresponding aldehydes with the aid of Wittig or Grignard reagents. The bicyclic-fused pyridines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosi.

US$29.90


Other references

Schmidt, J.; Snipes, W., 1967: Free radical formation in a gamma-irradiated pyrimidine-purine co-crystal complex. The formation and properties of free radicals in a co- crystal complex between 1-methylthymine and 9-methyladenine were studied by electron spin resonance spectroscopy. The radicals formed in this complex do not represent a simple composite of tho...

Burgess, Jr.; B.F., 1949: Surface Film Studies on DDT-Oil Larvicides. An account is given of tests of various petroleum oils and surface-active agents carried out with a view to improving the stability and spreading coefficients of DDT solutions for the control of Anopheline larvae. Film pressures were determined wi...

Nantel, J.; de Solages, C.; Bronte-Stewart, H., 2012: Repetitive stepping in place identifies and measures freezing episodes in subjects with Parkinson's disease. Freezing of gait (FOG) in Parkinson's disease (PD) is challenging to measure. We asked whether a repetitive stepping in place (SIP) task on force plates could identify freezing episodes (FEs) in PD subjects, self-classified as "freezers&...

Pfleiderer, H., 1933: Heat regulation in man. This paper contains a critical review with special reference to the work of Benedict and Root, Heller and Bohnenkamp. An account is given of the author's own investigations on the effect of the North Sea climate on average skin temperature, p...

Larsen, S.Arild.; Mogensen, L.; Dietz, R.; Baagøe, H.Jørgen.; Andersen, M.; Werge, T.; Rasmussen, H.Berg., 2005: Identification and characterization of tandem repeats in exon III of dopamine receptor D4 (DRD4) genes from different mammalian species. In this study we have identified and characterized dopamine receptor D4 (DRD4) exon III tandem repeats in 33 public available nucleotide sequences from different mammalian species. We found that the tandem repeat in canids could be described in a...

Tanaka, H.; Takeya, Y.; Doi, T.; Yumoto, F.; Tanokura, M.; Ohtsuki, I.; Nishita, K.; Ojima, T., 2005: Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I. Vertebrate troponin regulates muscle contraction through alternative binding of the C-terminal region of the inhibitory subunit, troponin-I (TnI), to actin or troponin-C (TnC) in a Ca2+-dependent manner. To elucidate the molecular mechanisms of th...

Selkurt, E.E.; Womack, I.; Dailey, W.N., 1965: Mechanism Of Natriuresis And Diuresis During Elevated Renal Arterial Pressure. Continuous perfusion of the dog's renal artery at pressures averaging 200 mm Hg resulted in natriuresis, increased osmolar clearance, and increase in urine volume. The diuresis was typified by a decrease in TC H2O, and in some instances posit...

Kwon, B.S.; Gangarosa, L.P.; Burch, K.D.; deBack, J.; Hill, J.M., 1981: Induction of ocular herpes simplex virus shedding by iontophoresis of epinephrine into rabbit cornea. Ocular herpes simplex virus type 1 (HSV-1) shedding from the latently infected rabbit was induced by iontophoresis of 0.01% epinephrine into the eye. The iontophoresis of epinephrine was at 0.8 mAmp for 8 min once a day for 3 consecutive days. She...

Hetman, J., 1977: Residual effect of nitrogen fertilization on the suitability of tulip bulbs for forcing and reproduction. N fertilization (120 or 240 kg N/ha) applied in the first year during the production of tulip bulbs (cvs General Eisenhower and Sonia) had a beneficial effect on forcing and on bulb yield in the second year of cultivation. N deficiency in the non-...

Kim, J.H.; Kim, J.K.; Choe, Y.K., 1998: Cloning and sequencing of the pyrG encoding cytidine 5'-triphosphate synthetase from Mycobacterium bovis BCG. The pyrG gene encoding cytidine 5'-triphosphate (CTP) synthetase which catalyzes the terminal reaction for de novo synthesis of pyrimidine nucleotides was cloned and sequenced from Mycobacterium bovis BCG. The BCG pyrG was screened in lambda...