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Contrast agents

, : Contrast agents. Official Gazette of the United States Patent & Trademark Office Patents 1273(4), Aug 26

The invention provides a composition of matter of the formula (I): V--L--R, where V is a vector moiety having affinity for an angiogenesis-related endothelias cell receptor, L is a linker moiety or a bond and R is a detectable moiety, characterized in that V is a non-peptidic organic group, or V is peptidic and R is a macromolecular or particulate species providing a multiplicity of labels detectable in in vivo imaging.


DOI: 10.1016/s0002-9149(01)01956-7

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