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Dietary glycemic index, glycemic load and insulin resistance in the Framingham Offspring Cohort

, : Dietary glycemic index, glycemic load and insulin resistance in the Framingham Offspring Cohort. FASEB Journal 17(4-5): Abstract No 437 1, March

The role of carbohydrate nutrition in the etiology of insulin resistance is poorly understood. One hypothesis is that greater intake of carbohydrates with high glycemic index (an indicator of carbohydrates ability to raise blood glucose) produces greater insulin resistance. Furthermore, the glycemic load, a measure of both the quality and quantity of carbohydrate in the diet, may be associated with insulin resistance. We examined the association between glycemic index and glycemic load on insulin resistance using the homeostasis model assessment (HOMA-IR) in 1289 men and 1544 women of the Framingham Offspring Cohort. HOMA-IR was calculated using the following formula: (fasting plasma insulin x plasma glucose)/22.5. After adjustment for age, sex, smoking dose, body mass index, waist-hip ratio, multi-vitamin use, treatment for blood pressure, alcohol intake, total energy intake, percentage saturated and polyunsaturated fat, the mean HOMA-IR values for ascending quintiles of glycemic index were 6.4, 6.7, 6.8, 6.8, 7.0 (P <0.001 for trend) and for ascending quintiles of glycemic load were 6.7, 6.5, 6.7, 6.8, 7.0 (P <0.05 for trend). These associations remained significant after further adjustment for cereal fiber. These data support the hypothesis that high glycemic index diets are associated with insulin resistance.


Other references

Calabrese, P.; Besleaga, T.; Eberhard, Aé.; Vovc, V.; Baconnier, P., 2007: Respiratory inductance plethysmography is suitable for voluntary hyperventilation test. The aim of this work was to evaluate the goodness of fit of a signal issued of the respiratory inductance plethysmography (RIP) derivative to the airflow signal during rest, voluntary hyperventilation, and recovery. RIP derivative signal was filte...

Bradley, J.D., 1956: Presence de la famille des Arrhenophanidae a Madagascar, avec descriptions de deux nouvelles especes (Lepidoptera). Revue Francaise d'Entomologie, 23: 132-135

Orlandella, V.; Alosi, C.; Campagna, A.; Ilacqua, G.; Coppola, L., 1972: Research on reservoirs of Toxoplasma gondii: study on the hedgehod Erinaceus eruopaeus var. Italicus, Barret-Hamilton 1900. Giornale di Batteriologia, Virologia Ed Immunologia Ed Annali Dell'ospedale Maria Vittoria di Torino. Parte 1: Sezione Microbiologica 65(1): 14-25

Asherson, G.L.; Dieli, F.; Sireci, G.; Salerno, A., 1996: Role of IL-4 in delayed type hypersensitivity. IL-4 plays a key role in the contact sensitivity skin reaction. This has several implications. First, the view that contact sensitivity (CS) is only mediated by cells with a Th1 profile of cytokine secretion needs modification, in the light of the...

Hu, F.; Niu, L.; Chen, R.; Ma, Y.; Qin, X.; Hu, Z., 2016: The association between social capital and quality of life among type 2 diabetes patients in Anhui province, China: a cross-sectional study. To investigate the association between social capital and quality of life among type 2 diabetes patients in Anhui province, China. In a cross-sectional study, 436 adults with type 2 diabetes were interviewed. The two domains of Quality of life, ph...

Hyams, R.L.; Carver, M.A.; Partis, M.D.; Griffiths, D.E., 1977: Studies of energy-linked reactions: oleoyl phosphate-dependent ATP synthesis (oleoyl phosphokinase) activity of membrane ATPase and soluble ATPases from mitochondria, chloroplasts, chromatophores, and Escherichia coli plasma membrane. Febs Letters 82(2): 307-313

Saunders, W.P.; Saunders, E.M., 1994: Comparison of three instruments in the preparation of the curved root canal using the modified double-flared technique. Fifty-one extracted intact human first molar teeth with mature root apices were radiographed in a standardized way; their root curvature was determined and they were divided into three groups. One root canal in the mesial root of the mandibular mo...

Wilson D.R.; Knox W.H.; Sax J.; Sen A.K., 1976: Effect of methyl prednisolone on renal sodium potassium atpase deficiency in the post obstructive kidney. Cook, John S (Ed ) Society Of General Physiologists Series, Vol 31 Biogenesis And Turnover Of Membrane Macromolecules Symposium Xxiv+280p Illus Raven Press: New York, N Y , U S A Isbn 0-89004-092-3 161-168

Brethour, J.R., 1966: Feeding wheat to beef cattle. (Kansas Agric. Exp. Stat. Bull. NO. 487). From experiments in which beef cattle were given wheat it is recommended that the wheat should be coarsely cracked and limited to 50% of the concentrate. In experiments with finely ground wheat, steam-rolled wheat or molasses added to wheat those...

Anonymous, 1987: Report of the Special Task Force on Professional Liability and Insurance and the Advisory Panel on Professional Liability. JAMA 257(6): 810-812