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Distinct phenotypes of MDA-MB-435/LCC6HER-2 and MCF-7HER-2 HER-2/neu overexpressing breast cancer xenograft models are linked to differential responses to treatment with trastuzumab and gefitinib


, : Distinct phenotypes of MDA-MB-435/LCC6HER-2 and MCF-7HER-2 HER-2/neu overexpressing breast cancer xenograft models are linked to differential responses to treatment with trastuzumab and gefitinib. Proceedings of the American Association for Cancer Research Annual Meeting 44: 314, July


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Perez-Ellis, C.; Goncalves, A.; Jacquemier, J.; Marty, M.; Girre, Véronique.; Roché, H.; Brain, E.; Moatti, J-Paul.; Viens, P.; L.C.rroller-Soriano, A-Gaëlle., 2013: Cost-effectiveness analysis of trastuzumab (herceptin) in HER2-overexpressed metastatic breast cancer. In women with Human Epidermal growth Receptor 2 (HER2)-positive metastatic breast cancer (MBC), Trastuzumab has become the standard of care but previous studies have raised doubts about its economic acceptability. We carried out the first cost-eff...

Schmitt, H.; Boucard, T.; Garric, J.; Jensen, J.; Parrott, J.; Péry, A.; Römbke, Jörg.; Straub, Jürg.Oliver.; Hutchinson, T.H.; Sánchez-Argüello, P.; Wennmalm, A.; Duis, K., 2011: Recommendations on the environmental risk assessment of pharmaceuticals: Effect characterization. The effects testing of pharmaceuticals consists of a tiered investigation of ecotoxicological endpoints. However, effects testing has to be performed only when the predicted environmental concentrations (PECs) of pharmaceuticals are above certain...

Chou, C-Chi.; Rajasekaran, M.; Chen, C., 2010: An effective approach for generating a three-Cys2His2 zinc-finger-DNA complex model by docking. Determination of protein-DNA complex structures with both NMR and X-ray crystallography remains challenging in many cases. High Ambiguity-Driven DOCKing (HADDOCK) is an information-driven docking program that has been used to successfully model ma...

Ogawa, Y.; Sugawara, T.; Seki, H.; Sakuma, T., 2006: Thyroid follicular carcinoma metastasized to the lung, skull, and brain 12 years after initial treatment for thyroid gland--case report. A 65-year-old woman presented with multiple metastases from thyroid follicular carcinoma to the lung, skull, and brain. The skull and brain tumors had been successfully treated by surgery, thyroxine supplementation, and radiosurgery until she died...

Fernandez Riva, J., 1988: Fruit and vegetable processing in Colombia. This paper follows on from work published in Revista Nacional de Agricultura Nos. 881 and 882. An overview of Colombian agroindustry is presented and a classification into basic, advanced and export-based agroindustry is proposed. The subsectors a...

Marcangeli, Jorge A., 2002: Evaluation of the modifiqued technique of drone trap comb to control the mite Varroa destructor in honeybee colonies of Apis mellifera. The objective of the work was to evaluate the technique of drone trap-brood using two drone brood frames in replace of five proposed by other authors. The work was done on a commercial apiary located at Coronel Vidal city, province of Buenos Aires...

Pazmino, P.A., 2016: Current Concepts on Diabetic Nephropathy and 2014 Data on Diabetic Renal Failure in Texas. Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD) in the United States and other developed countries. In 1982, diabetes accounted for 27% of patients with ESRD in the United States and rose to 36% by 1992 and to 47%...

Ta, N.; Hong, J.; Liu, T.; Sun, C., 2006: Degradation of atrazine by microwave-assisted electrodeless discharge mercury lamp in aqueous solution. The present study investigates the degradation of atrazine (2-chloro-4-(ethyl amino)-6-isopropyl amino-s-triazine) in aqueous solution by a developed new method, namely by means of a microwave-assisted electrodeless discharge mercury lamp (MW-EDM...

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