+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of high carbohydrate diets on the physical-chemical properties of plasma lipoproteins in hamsters

, : Effects of high carbohydrate diets on the physical-chemical properties of plasma lipoproteins in hamsters. FASEB Journal 17(4-5): Abstract No 196 2, March

High carbohydrate diets can reduce plasma LDL cholesterol or provoke the appearance of the atherogenic lipoprotein profile, ALP. ALP consists of high plasma triacylglycerol, TAG, small dense LDL and reduced HDL cholesterol in association with insulin resistance. At present it is unknown whether the oft used fructose-fed hamster model of insulin resistance exhibits all features of ALP. Therefore, we investigated the metabolic and physical-chemical properties of lipoproteins in hamsters fed diets containing either 60% fructose (HF) or 60% starch (S) for 2 weeks. Hamsters fed HF showed significantly (p< 0.05) increased VLDL-TAG (92.3%), free cholesterol (68.6%), and phospholipid (95%) while apoB remained unchanged. Circulating VLDL diameter was slightly larger (68 vs. 63nm, p=0.08) in HF fed as compared to S fed hamsters. Fructose feeding induced a 42.5% increase in LDL-TAG (p<0.05) at the expense of a 20% reduction in LDL-cholesteryl ester (p<0.05). Compositional changes were associated with reduced LDL diameter (23.97 vs. 24.40 nm, p < 0.05). In contrast, HF caused significant elevations in all HDL lipid fractions and HDL-protein (p <0.05). Apo-B containing lipoproteins exhibit similar physical properties in HF fed hamsters and humans with ALP. However, HDL metabolism appears to respond differently and may be due to species differences.


Other references

Duncan, W.H.; Way, N., 2008: The founders of the Medical Society of Delaware: Doctor Nicholas Way. Delaware Medical Journal 80(8): 301-303

Classen, S.; Krasniuk, S.; Morrow, S.A.; Alvarez, L.; Monahan, M.; Danter, T.; Rosehart, H., 2017: Visual Correlates of Fitness to Drive in Adults With Multiple Sclerosis. The impact of visual and visual-cognitive impairments on fitness to drive in persons with multiple sclerosis (PwMS) are not well studied. We quantified visual correlates of fitness to drive in 30 PwMS. PwMS completed visual ability and visual atte...

Shenhav, A.; Mendes, W.Berry., 2014: Aiming for the stomach and hitting the heart: dissociable triggers and sources for disgust reactions. Disgust reactions can be elicited using stimuli that engender orogastric rejection (e.g., pus and vomit; core disgust stimuli) but also using images of bloody injuries or medical procedures (e.g., surgeries; blood [body] boundary violation [B-BV]...

Lee, H-Ah.; Lee, J-Hyeok.; Han, J-Sook., 2017: A phlorotannin constituent of Ecklonia cava alleviates postprandial hyperglycemia in diabetic mice. 2,7″-Phloroglucinol-6,6'-bieckol is a type of phlorotannin isolated from brown algae, Ecklonia cava Kjellman (Phaeophyceae; Laminareaceae). 2,7″-Phloroglucinol-6,6'-bieckol mediates antioxidant activities. However, there has been no...

Doi, Y.; Furuno, T.; Kubo, T.; Yamasaki, N.; Kitaoka, H., 2015: Cardiovascular disease in the elderly: Management of atrial fibrillation and chronic heart failure. Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics 51(3): 218-221

Rabes, O., 1901: Ueber Transplantationsversuche an Lumbriciden. Biologisches Zentralblatt, XXI 633-650

Guedeney, A.; Guedeney, N.; Tereno, S.; Dugravier, R.; Greacen, T.; Welniarz, B.; Saias, T.; Tubach, F.; Azria, E.; Barranger, E.; Bénifla, J-Louis.; Carbonne, B.; Dommergues, M.; Dugravier, R.; Falissard, B.; Greacen, T.; Guédeney, A.; Guédeney, N.; Haddad, A.; Luton, D.; Mahieu-Caputo, D.; Mandelbrot, L.; Oury, J-François.; Pathier, D.; Purper-Ouakil, D.; Saïas, T.; Tereno, S.; Tremblay, R.; Tubach, F.; Uzan, S.; Welniarz, B., 2012: Infant rhythms versus parental time: promoting parent-infant synchrony. Traditional psychoanalytic theories of early development have been put into question by developmental psychology, and particularly by attachment theory. Psychopathology appears to be more linked to interpersonal relationship problems rather than t...

Cobe, Patricia, 1977: Falling in love with vegetables. Hands on preparation of good looking and tasting vegetable dishes will help children learn that vegetables are delicious. Nine photographs are provided of an eighth grade class in home economics preparing spinach ricotta dumplings, vegetables temp...

Proppe D., 1968: Role of the sympathico adreno medullary system in thermoregulation in baboons abstract. Proc Int Union Physiol Sci: 147

Tindel, M.; Lavillaureix, J.; Singer, L., 1975: Mental hygiene and habitat. Problem of large developments in relation to an epidemiological study carried out at Mulhouse. Annales Medico-Psychologiques 2(1): 31-63