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Imaging neural activity with temporal and cellular resolution using FISH

, : Imaging neural activity with temporal and cellular resolution using FISH. Current Opinion in Neurobiology 11(5): 579-584

Immediate early genes have gained widespread use as neural activity markers in studies of brain function. The recent development of cellular compartment analysis of temporal activity, which combines sensitive fluorescence in situ hybridization and laser scanning confocal microscopy, overcomes the lack of temporal resolution of standard methodologies and allows the tracking of distinct steps in the synthesis and processing of immediate early gene RNAs. Thus, this technique provides information about when individual neurons are activated and allows the visualization, within a single brain, of different neuronal populations engaged by two distinct experiences.


PMID: 11595491

DOI: 10.1016/s0959-4388(00)00252-x

Other references

Barranger, J.A., 1993: Gaucher's disease: new hope for treatment. Lancet 342(8883): 1372-1372

Breithardt, G.; Borggrefe, M.; Karbenn, U.; Abendroth, R.R.; Yeh, H.L.; Seipel, L., 1982: Prevalence of late potentials in patients with and without ventricular tachycardia: correlation with angiographic findings. Late potentials occurring at the end of or after the QRS complex were searched for from the body surface using high gain amplification and signal averaging techniques with filter settings between 100 and 300 hertz. The number of repetitions of the...

Wetzel, R., 1932: Beziehungen parasitischer Wurmer zum Wirt. Munchenoch: 1381

Geissler, R.G.; Ganser, A.; Muth, J.; Engels, J.W.; Hoelzer, D., 1994: Antisense oligodeoxynucleotides against HIV-TAT-sequence protect hematopoietic bone marrow cells from HIV-mediated hematopoietic failure. British Journal of Haematology 87(SUPPL 1): 70

Tejedor A.; Noel J.; Boulanger Y.; Vinay P.; Gougoux A., 1986: Metabolism of isolated nephron segments in vitro relation between cell work and atp turnover. Journal of Clinical Chemistry & Clinical Biochemistry 24(9): 669

Emile, J.F.; Fraitag, S.; Leborgne, M.; de Prost, Y.; Brousse, N., 1994: Langerhans' cell histiocytosis cells are activated Langerhans' cells. Langerhans' cell histiocytosis (LCH) is characterized by the presence of large mononucleated cells, associated with inflammatory cells. The Langerhans' cell (LC) lineage of the mononucleated cells is suggested by the presence of Birbeck...

Kato, H.; Nakajima, M.; Ohnaka, Y.; Ishihara, K.; Kawamura, M., 2011: Recurrent abducens nerve palsy associated with neurovascular compression. We report a 50-year-old man who suffered from 5 transient diplopia episodes in 16 months. His diplopia lasted between 2 weeks and 3 months and examination revealed isolated left abducens palsy during the attacks of diplopia. Magnetic resonance (MR...

Shivers R.R., 1978: The blood brain barrier of a reptile anolis carolinensis studied with freeze fracture. Canadian Federation Of Biological Societies Proceedings: 62

Anonymous, 2014: Best of times, worst of times. Nature Reviews. Microbiology 12(6): 391-391

Hartwagner, A.; Ludvan, M., 1971: Microbial eczemas and diabetes mellitus. Zeitschrift für Haut- und Geschlechtskrankheiten 46(19): 634-637