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Inhibition of complement pathway by sea cucumber fractions

, : Inhibition of complement pathway by sea cucumber fractions. Official Gazette of the United States Patent & Trademark Office Patents 1228(4), Nov 23

The present invention relates to methods for inhibiting the complement pathway in a mammal comprising administering an effective dose of a composition comprising an active ingredient selected from the group consisting of isolated sea cucumber (Phylum Echinodermata, Class Holothuroidea) body wall, isolated sea cucumber epithelial layer, isolated sea cucumber flower, sea cucumber fucosylated chondroitin sulfate, combinations thereof, active derivatives thereof or combinations of active derivatives thereof.


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Heinzelmann, M.; Bosshart, H., 2004: Fondaparinux sodium lacks immunomodulatory effects of heparin. Venous thromboembolism (VTE) remains a frequent complication in orthopedic and trauma patients, despite the use of prophylactic antithrombotic drugs like standard or low molecular weight heparin. A new synthetic pentasaccharide with specific anti-...

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Chapman, H.H., 1941: Note on the history of a stand of pine timber at Urania, La. A virgin stand of longleaf pine (Pinus palustris) was found to contain only 3 age classes. Veterans 260 yrs. old had been partially displaced by medium sized trees 117 yrs. old after a hurricane and probably fire had opened up the stand. Younger t...