geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Latent effects of resveratrol exposure on adult male reproductive physiology and behavior


, : Latent effects of resveratrol exposure on adult male reproductive physiology and behavior. Society for Neuroscience Abstracts 27(1): 506

Resveratrol (RES), a major constituent of wine, has been linked to the cardiovascular benefits of drinking red wine. This phytoestrogen binds to and activates gene transcription via the ERalpha and ERbeta sub-types. We have previously shown that RES treatment has estrogenic effects on adult female physiology and behavior that may alter gonadotropin secretion patterns. The present study examines the effects of postnatal RES exposure during suckling on subsequent adult male reproductive physiology and behavior. Males pups were exposed to RES from PND 1-21 via maternal consumption of RES (5muM, 50muM, or 100muM) in daily drinking water. At PND 132, males were tested for sociosexual behavior with estrous female partners. Immediately after testing, brains and plasma were collected and reproductive organs were weighed and analyzed. Compared to controls, postnatal RES exposure decreased the frequency of mounting behavior towards sexually receptive stimulus females and increased testes weight without effects on preputial glands and seminal vesicles in adult males. Postnatal RES exposure also produced a dose-dependent decrease in cell counts of the SDN-POA and in plasma testosterone levels. These findings suggest that postnatal RES exposure may have altered cellular activities in the MPOA that could compromise male typical patterns of gonadotropin secretion, thus feminizing sociosexual behavior in males.

US$29.90


Other references

Van Nostran, Frederick E., 1959: Physiological activities in Sporodinia grandis Link. Dissertation Absts 19(7): 1536

Cuena J.; Custodio E., 1974: Construction and adjustment of a two-layer mathematical model of the Llobregat Delta. Studies and Reports in Hydrology = Etudes et Rapports d'Hydrologie = Estudios e Informes de Hidrologia = Issledovaniya i Doklady po Gidrologii 15, Mathematical models in hydrology): 950-964

Lawson, Zë.; Nuttall, D.; Young, S.; Evans, S.; Maguire, S.; Dunstan, F.; Kemp, A.M., 2012: Which is the preferred image modality for paediatricians when assessing photographs of bruises in children?. Images of bruises serve as a clinical record and may facilitate forensic analysis in the assessment of suspected physical child abuse. Currently, only conventional imaging techniques are employed; however, alternative imaging modalities using visi...

Giavazzi, R.; Garofalo, A.; Bani, M.R.; Abbate, M.; Ghezzi, P.; Boraschi, D.; Mantovani, A.; Dejana, E., 1990: Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice. This study has examined the effect of the cytokine interleukin 1 (IL-1) on metastasis formation by the human melanoma A375M in nude mice. We have found that human recombinant IL-1 beta (a single injection greater than 0.01 micrograms per mouse i.v...

Holman, GM.; Cook, BJ., 1979: The analytical determination of proctolin by HPLC and its pharmacological action in the stable fly. A method utilizing high performance liquid chromatography as a purification technique and for quantitative analysis of proctolin (Arg-Tyr-Leu-Pro-Thr) in whole-body extracts of the stable fly, Stomoxys calcitrans (L.) was developed. Analysis of ne...

Schilling, E.C.rne, F., 1972: Hormonal triggering of premature puberty in young sows. Tierzuchter 24 (24) 714-715

Ramon, G.; Richou, R.; Julienne, P.; Jacquet, J.; Gerbeaux, C., 1951: Development of staphylococcic antitoxin in bovines subjected to injections of specific anatoxin. Comptes Rendus Hebdomadaires des Seances de L'academie des Sciences 233(16): 833-836

Hanna, M.H.; Jafari, M.D.; Jafari, F.; Phelan, M.J.; Rinehart, J.; Sun, C.; Carmichael, J.C.; Mills, S.D.; Stamos, M.J.; Pigazzi, A., 2017: Randomized Clinical Trial of Epidural Compared with Conventional Analgesia after Minimally Invasive Colorectal Surgery. The effectiveness of thoracic epidural analgesia (EA) vs conventional IV analgesia (IA) after minimally invasive surgery is still unproven. We designed a randomized controlled trial comparing EA with IA after minimally invasive colorectal surgery....

Donoghue, P.C.J.; Benton, M.J., 2007: Rocks and clocks: calibrating the Tree of Life using fossils and molecules. A great tradition in macroevolution and systematics has been the ritual squabbling between palaeontologists and molecular biologists. But, because both sides were talking past each other, they could never agree. Practitioners in both fields should...

Mangold, K.; Von-Boletzky, S.; Frosch, D., 1971: Reproductive biology and embryonic development of eledone cirrosa cephalopoda octopoda. Marine Biology (Berlin) 8(2): 109-117