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Magnetic stretching of magnetized neurons for spinal cord or peripheral nerve repair and regeneration

, : Magnetic stretching of magnetized neurons for spinal cord or peripheral nerve repair and regeneration. Official Gazette of the United States Patent & Trademark Office Patents 1239(3), Oct 17

A severed or otherwise interrupted spinal cord or peripheral nerve is provided with magnetic nanoparticles which are absorbed or actively incorporated into the neurons and their axons. The severed or otherwise interrupted nerve or cord is then exposed to an external magnetic field which is moved longitudinally of the severed or otherwise interrupted nerve or spinal cord, thereby stretching the magnetic particle-loaded neurons and their axons along the desired axis for bridging the gap or gaps and repairing the injured spinal cord or nerve. The procedure may be repeated to extend the area of repair. The severed or otherwise interrupted spinal cord or peripheral nerve is advantageously provided, either internally or alongside, with an insert comprising multiple strands of biodegradable material having magnetic particles oriented along the axis thereof, for focusing and concentrating the external magnetic field in the desired axis. Magnetic particles tagged with substances which are biologically incorporated into neurons and their axons may be employed to increase the absorption of the magnetic particles into the cells and/or to stimulate the growth activities of the cell.


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