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P35/Cdk5 phosphorylates RasGRF2 regulating RasGRF2-mediated Rac signaling and ERK1/2 activity


, : P35/Cdk5 phosphorylates RasGRF2 regulating RasGRF2-mediated Rac signaling and ERK1/2 activity. Journal of Neurochemistry 88(Supplement 1): 81, February


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Taga, Y.; Miyoshi, M.; Okajima, T.; Matsuda, T.; Nadano, D., 2010: Identification of heterogeneous nuclear ribonucleoprotein A/B as a cytoplasmic mRNA-binding protein in early involution of the mouse mammary gland. Involution of the mammary gland is a regressive phase that occurs after lactation, and requires reprogramming of gene expression for the tissue to return to a pre-pregnant state. Although the transcriptome of the mammary gland demonstrates complex...

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Rando, G.; Schibler, U., 2014: Glucocorticoid rhythm renders female mice more daring. Glucocorticoids, which have been implied in mood modulation, display robust diurnal oscillations in the blood. But does their circadian rhythm regulate mood swings? Ikeda et al. now identify a paracrine signaling pathway in the adrenal cortex that...

Jia Yu, R.; Boucot, A.J., 1998: A global review of the Virgianidae. A review of the Late Ordovician, chiefly mid-Ashgillian, to Early Silurian, Llandoverian, pentameroidean brachiopods, the Virgianidae, permits them to be assigned to three subfamilies (Virgianinae (10 genera assigned), Mariannaellinae (5 genera as...

Karpuk, N.N.; Vorob'ev, V.V., 2003: Dependence of different spike sequences on the mean neuronal firing rate in the neocortex in vivo and in vitro. Neuronal spikes were recorded extracellularly in rabbit visual cortex in vivo (88 cells) and in surviving slices of guinea pig sensorimotor cortex in vitro (50 cells). Spike sequences (SS) with monotonically increasing (SS+) and decreasing (SS-) i...

Yoo, J.Hyuk.; Cheong, M.Sun.; Park, C.Young.; Moon, B.Cheol.; Kim, M.Chul.; Kang, Y.Hwan.; Park, H.Cheol.; Choi, M.Soo.; Lee, J.Huck.; Jung, W.Yong.; Yoon, H.Won.; Chung, W.Sik.; Lim, C.Oh.; Lee, S.Yeol.; Cho, M.Je., 2003: Regulation of the dual specificity protein phosphatase, DsPTP1, through interactions with calmodulin. Reversible phosphorylation is a key mechanism for the control of intercellular events in eukaryotic cells. In animal cells, Ca2+/CaM-dependent protein phosphorylation and dephosphorylation are implicated in the regulation of a number of cellular p...