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P38MAPK inhibitor and uses thereof

, : P38MAPK inhibitor and uses thereof. Official Gazette of the United States Patent & Trademark Office Patents 1273(1), Aug 5

The present invention demonstrates that p38MAPK inhibitor induces low density lipoprotein receptor expression 6-8 fold, and further provides the application of such inhibitor in the treatment of hypercholesterolemia.


Other references

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Zhao, W-wu.; Fu, B-jie.; Meng, Q-hua.; Zhang, Q-ju.; Zhang, Y-hui., 2004: Effects of land-use pattern change on rainfall-runoff and runoff-sediment relations: a case study in Zichang watershed of the Loess Plateau of China. The purpose of this article was to identify the effect of land use pattern on rainfall-runoff and runoff-sediment relations in Zichang Watershed of the Loess Plateau, Shaanxi Province, China. From 1986 to 1997, many farmlands changed into grasslan...

Wang, Y-Q.; Wang, M-Y.; Fu, X-R.; Peng-Yu; Gao, G-F.; Fan, Y-M.; Duan, X-L.; Zhao, B-L.; Chang, Y-Z.; Shi, Z-H., 2016: Neuroprotective effects of ginkgetin against neuroinjury in Parkinson's disease model induced by MPTP via chelating iron. Disruption of neuronal iron homeostasis and oxidative stress are closely related to the pathogenesis of Parkinson's disease (PD). Ginkgetin, a natural biflavonoid isolated from leaves of Ginkgo biloba L, has many known effects, including anti...

Garvey, James E., 2003: Searching for Scales in Fisheries. BioScience 53(10): 04, 1006

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Lemaitre, Rafael, 2004: A review of Strobopagurus Lemaitre, 1989 (Crustacea: Decapoda: Paguroidea: Parapaguridae), with description of a new species. Species of the parapagurid genus Strobopagurus Lemaitre, 1989 are reviewed based primarily on abundant specimens obtained during French campaigns across the Indo-Pacific region. A new species, S. breviacus, is described. The genus contains two oth...

Schwartges, I.; Picker, O.; Beck, C.; Scheeren, T.W.L.; Schwarte, L.A., 2011: Hypercapnic acidosis preserves gastric mucosal microvascular oxygen saturation in a canine model of hemorrhage. The authors aimed to clarify the effects of hypercapnic acidosis and its timing on gastric mucosal oxygenation in a canine model of hemorrhage. This was designed as a prospective, controlled, randomized animal study set in a university research la...

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