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Cardiovascular implications of antihyperglycemic therapies for type 2 diabetes

, : Cardiovascular implications of antihyperglycemic therapies for type 2 diabetes. Clinical Therapeutics 33(4): 393-407

Risk factors for cardiovascular disease (CVD), including insulin resistance/hyperinsulinemia, hyperglycemia, overweight/obesity, dyslipidemia, and hypertension, are often present in varying combinations in patients with type 2 diabetes mellitus (DM). Patients with a clustering of these risk factors, termed the metabolic syndrome, are at greater risk for CVD than are patients with only a single risk factor. Although glycemic control is the central feature of type 2 DM management, patients require an individualized approach to therapy that takes their other CVD risk factors into account. This review examined the effects of antidiabetes therapy on glycemic control, as well as its potential to.


PMID: 21635987

DOI: 10.1016/j.clinthera.2011.04.006

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