geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Cell types, circuits, computation


, : Cell types, circuits, computation. Current Opinion in Neurobiology 21(5): 664-671

How does the connectivity of a neuronal circuit, together with the individual properties of the cell types that take part in it, result in a given computation? We examine this question in the context of retinal circuits. We suggest that the retina can be viewed as a parallel assemblage of many small computational devices, highly stereotypical and task-specific circuits afferent to a given ganglion cell type, and we discuss some rules that govern computation in these devices. Multi-device processing in retina poses conceptual problems when it is contrasted with cortical processing. We lay out open questions both on processing in. Highlights: The retina can be viewed as a parallelized array of functionally distinct computational devices. Each device, a neuronal circuit, is assembled from a small subset of cell types. Key elements of computation are the dynamics of inhibition and the nonlinearities. An open question: How do cortical circuits process the multiple retinal outputs?

US$19.90

PMID: 21641794

DOI: 10.1016/j.conb.2011.05.007


Other references

Charlie, R.E.; Clarkson, P.L., 2000: Working together and using all knowledge to manage renewable resources in the Gwichin Settlement Area. Arctic Science Conference Abstracts 51: 35-36

Hyttinen, J.M.T.; Myohanen, S.; Jansson, K., 1996: Kinds of mutations induced by 3-chloro-4- -5-hydroxy-2 -furanone in the hprt gene of Chinese hamster ovary cells. The kinds of mutations induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in the protein coding region of the hprt gene of Chinese hamster ovary (CHO) cells were determined by direct sequencing of polymerase chain reaction (PCR)-...

Ozaki, K.; Kurosu, Y., 1967: Resistance pattern in four strains of insecticide-resistant green rice leafhopper, Nephotettix cincticeps Uhler, collected in fields. The following is substantially the English summary. One susceptible and four insecticide-resistant strains of Nephotettix cincticeps (Uhl.) were collected from rice-fields in Japan in the summer and autumn of 1963, and the LD50's of 17 insect...

Cinciripini, Paul M., 1995: Current trends in smoking cessation research Psychological therapy, nicotine replacement, and changes in smoking behavior. Cancer Bulletin (Houston) 47(3): 259-263

Moser R.P.Jr; Wagner G.N., 1990: Nutrient groove of the ilium a subtle but important forensic radiographic marker in the identification of victims of severe trauma. A variety of skeletal characteristics pertaining to the bony pelvis have, over the years, been of assistance as forensic markers, but the importance of the nutrient groove of the ilium has not been appreciated. During aircraft accident investigati...

Baum, C.; Haslinger-Löffler, B.; Westh, H.; Boye, K.; Peters, G.; Neumann, C.; Kahl, B.C., 2010: Non-spa-typeable clinical Staphylococcus aureus strains are naturally occurring protein A mutants. Staphylococcus aureus is a major human pathogen responsible for increasing the prevalence of community- and hospital-acquired infections. Protein A (SpA) is a key virulence factor of S. aureus and is highly conserved. Sequencing of the variable-nu...

Uchiyama, T.; Kulkarni, A.A.; Davies, D.L.; Lee, V.H.L., 2004: Biophysical evidence for His57 as a proton-binding site in the mammalian intestinal transporter hPepT1. The objective of this study was to provide direct evidence of the relative importance of the His57 residue present in transmembrane domain 2 (TMD 2) and the His121 residue in TMD 4 as proton-binding sites in human PepT1 (hPepT1) by using a novel m...

Reinken, L.; Hohenauer, L.; Ziegler, E.E., 1972: Activity of redd cell glutamic oxalacetic transaminase in epileptic children under antiepileptic treatment. Clinica Chimica Acta; International Journal of Clinical Chemistry 36(1): 270-271

Amarin M.; Jones B.R., 1988: Fine structure of sensory nerve endings in schistosome miracidia. FASEB Journal 2(6): ABSTRACT 8364

Chen, C-Pin.; Chen, C-Tin.; Tsai, T., 2012: Chitosan nanoparticles for antimicrobial photodynamic inactivation: characterization and in vitro investigation. The growing resistance to antibiotics rendered antimicrobial photodynamic inactivation (PDI) an attractive alternative treatment modality for infectious diseases. Chitosan (CS) was shown to further potentiate the PDI effect of photosensitizers (PS...