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Diffusion-weighted MR-imaging for the detection of pulmonary nodules at 1.5 Tesla: intraindividual comparison with multidetector computed tomography

, : Diffusion-weighted MR-imaging for the detection of pulmonary nodules at 1.5 Tesla: intraindividual comparison with multidetector computed tomography. Journal of Medical Imaging and Radiation Oncology 55(3): 266-274

To investigate the feasibility of diffusion-weighted imaging (DWI) MRI for detecting pulmonary nodules at 1.5 Tesla in comparison with standard multidetector computed tomography (MDCT).Twenty patients with disseminated cancer disease in which MDCT had assured the presence of at least one pulmonary nodule were examined using a respiratory-gated DWI MR-sequence. Grey scale inverted source images and coronal maximum intensity projection (MIP) images were consensually analysed by two experienced radiologists. Size and location of any nodule detected were assessed. Additionally, the readers evaluated each hemithorax for the presence of at least one nodule and applied a four-point conspicuity scale (1-hemithorax definitely affected; 4-hemithorax definitely not affected). MDCT data served as reference. At MDCT, a total of 71 pulmonary noduIes was found (size 3 5 mm, n = 16; 6 9 mm, n = 22; ?1 mm, n = 33). For the DWI MR-sequence, a sensitivity of 86.4% was calculated for nodules ranging 6 9 mm and 97% for nodules ?1 mm. In contrast, only 43.8% of lesions ?5 mm was detected. The separate analysis of each hemithorax for the presence of at least one pulmonary nodule revealed a specificity rate, PPV and NPV of DWI-MR of 92.3%, 96% and 8%, respectively.The presented study is the first to confirm the diagnostic potential of DWI-MR in the detection of solid lung nodules. This technique allows for the detection of nodules ?6 mm with reasonably high sensitivity rates (>86%). The observation of false positive findings decreases the accuracy of this approach compared with MDCT.


PMID: 21696559

DOI: 10.1111/j.1754-9485.2011.02263.x

Other references

Moore, A., 2012: General Practice. Your money or your life. Health Service Journal 121(6276): 27-28

Lai, C.; Wang, D-Jun.; Duan, C-Kui.; Xia, S-Da., 2008: The fluctuation of radiative lifetime of dielectric luminescent-ion-containing nanoparticles randomly distributed in media. The radiative lifetime of an emitter (such as a luminescent ion) is affected not only by the properties of the emitter itself but also by the dielectric properties of the surrounding media. The fluctuation of the local electrical field caused by r...

Duñgog, E.F., 1982: Contributions of research in the future directions for the care of the disabled. Anphi Papers 17(1-2): 1-2

Beranek, J.T., 1991: Histogenesis of intimal hyperplasia and arterial dissection. Journal of Vascular Surgery 13(1): 176-177

Anderson, J.; Niekerk, P.J. van, 1987: High-performance liquid chromatographic determination of antioxidants in fats and oils. A simple procedure is reported which requires neither extraction nor derivatization for the direct estimation of the antioxidants BHA (3-tert.-butyl-4-hydroxyanisole), PG (propyl gallate), OG (octyl gallate), DG (dodecyl gallate), TBHQ (tert.-buty...

Meisel, M.N.; Remezova, T.; Medvedeva, G.A.; Pomoshchnikova, N.A.; Poglazova, M.N., 1964: On The Nature Of Structures Obtained By V. O. Kalinenko In Distilled Water Under The Influence Of An Electric Current. Mikrobiologiia 33: 364-367

Istasse L.; Rollin F.; Djiele N.K.; Van Eenaeme C.; Biston L.; Bienfait J.M., 1989: Discriminating power of the nylon bag technique and the pepsin cellulase method to detect less commonly used components included in concentrates for dairy cows. The nylon bag technique and the pepsin-cellulase method were used to detect the presence of fat and protein of low degradability in concentrates for dairy cows. Protected or non-protected fat and formaldehyde-treated soya bean meal or fish meal we...

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