geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis


, : Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis. Research in Veterinary Science 92(3): 492-493

This report describes the inhibition of the proteolytic activity of Haemonchus contortus lysate by a mixture of n-alkyl ferulates isolated from Maprounea guianensis. These compounds were evaluated in vitro for the ability to inhibit the H. contortus proteases using SDS PAGE copolymerized with gelatine (zymography) and by assaying the hemoglobinolytic activity of these enzymes in solution. The ferulates abrogated the proteolysis compared to E-64, suggesting the activity is the result of a cysteine protease.

US$19.90

PMID: 21757211

DOI: 10.1016/j.rvsc.2011.06.001


Other references

Poewe, W., 1993: Clinical and pathophysiologic aspects of late levodopa failure. More than 50% of all patients with Parkinson's disease who initially receive treatment with conventional levodopa will develop late complications, although the underlying mechanisms are not completely understood. Some aspects of levodopa peri...

Alcaide D.Pucci, Maria F., 1992: Histomorphological aspects of Leptodactylus chaquensis oviducts preovulatory period. The oviduct of the Leptodactylus chaquensis (Cei) in pre-ovulatory period is studied in differents macroscopical and microscopical sectors. Of each one of them, a detail is made, over his cellular and tissular constituent.

Domingues, C.E.F.; Olivera, C.M.C.; Oliveira, B.V.; Juste, F.S.; Andrade, C.R.F.; Giacheti, C.M.; Moretti-Ferreira, D.; Drayna, D., 2014: A genetic linkage study in Brazil identifies a new locus for persistent developmental stuttering on chromosome 10. Although twin, adoption, and family studies demonstrate that genetic factors are involved in the origins of stuttering, the mode of transmission of the disorder in families is not well defined and stuttering is considered a genetically complex tra...

Ferraro, D., O.; Ghersa, C., M., 2007: Exploring the natural and human-induced effects on the assemblage of soil microarthropod communities in Argentina. In order to determine the independent and joint effects of: (1) crop management; (2) soil condition; and (3) site location on soil biota assemblage, we examined the effects of several crop management and soil condition descriptors on the abundanc...

Yang, H.; Parniak, M.A.; Hillier, S.L.; Rohan, L.C., 2012: A thermodynamic study of the cyclodextrin-UC781 inclusion complex using a HPLC method. NlmCategory="UNASSIGNED">UC781, a very potent HIV-1 non-nucleoside reverse transcriptase inhibitor with extreme hydrophobicity and poor water solubility, is under development as a topical vaginal microbicide product to prevent HIV tra...

Javitt, D.C., 2010: Sensory processing in schizophrenia: neither simple nor intact. This special issue focuses on the theme of sensory processing dysfunction in schizophrenia. For more than 50 years, from approximately the time of Bleuler until the early 1960s, sensory function was considered one of the few preserved functions in...

Opell, Brent D., 1994: Factors affecting the diameters of axial fibers in Cribellar threads of the spider family Uloboridae. The diameters of axial fibers that support the cribellar threads of uloborids are shown by electron microscopy to be related to web architecture. Cribellar threads produced by the simple-web species Miagrammopes animotus and M. sp. are supported b...

Kassem, M.A.; Massoud, M.H., 1967: On the dosing of liquids according to the drop method. Il Farmaco; Edizione Pratica 22(2): 107-116

Elegado, F.B.; Guerra, M.Antonette.Ruth.V.; Macayan, R.A.; Mendoza, H.A.; Lirazan, M.B., 2004: Spectrum of bacteriocin activity of Lactobacillus plantarum BS and fingerprinting by RAPD-PCR. The spectrum of antimicrobial activity of Lactobacillus plantarum BS against representative bacterial species was established through deferred assay and 'spot-on-lawn' assay using actively growing cells and partially purified bacteriocin...

Meyer Franz O., 1989: Siliciclastic influence on Mesozoic platform development; Baltimore Canyon trough, western Atlantic. Special Publication - Society of Economic Paleontologists and Mineralogists 44: 213-232