geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A review of current management of brain metastases


, : A review of current management of brain metastases. Annals of Surgical Oncology 19(3): 1043-1050

The brain metastasis (BM) represents one of the most common and refractory malignancies worldwide with a rising incidence in all countries. It is generally believed that once a BM has developed, this disease cannot be cured and has a poor prognosis. The challenges of managing this tumor include diagnosis and selective treatment options. In addition, patients with BM frequently have greater expectations of the current therapy outcomes, which hope to get long-term survival and good quality of life. This is a review of current clinical practice based on an exhaustive literature search of PubMed, Embase, and Google Scholar. A series of case studies is presented to provide outcomes of the effective management in BMs that have required treatment for the terminal stage of patients with cancer, and makes recommendations for future practice. Current technical advances have been made in the diagnosis and treatment of BM. After surgery, radiotherapy, or stereotactic radiosurgery, and for some cases additional systemic chemotherapy for the primary cancer, most patients experience meaningful symptom relief, improved quality of life and longer survival time. An evidence-based summary of recommendations has been produced to guide neurosurgeons and oncologists in managing this particular group of patients. On the basis of the available data, this treatment approach for well-selected patients is currently not recommended in the treatment of BMs except in experienced medical centers. Clinical judgment is made balancing surgical, radiotherapy, chemotherapy and management principles to advocacy the best therapy outcome.

US$19.90

PMID: 21861219

DOI: 10.1245/s10434-011-2019-2


Other references

Ricciardolo, F.L.M., 2003: Multiple roles of nitric oxide in the airways. Nitric oxide is endogenously released in the airways by nitric oxide synthase. Functionally, two isoforms of this enzyme exist: constitutive and inducible. The former seems to protect airways from excessive bronchoconstriction while the latter has...

Kochetkov A.Ya, 1970: Intrusion phases and facies varieties of granitoids in the Bay-Tayga massif (western Tuva). English translation of Fazy intruzii i fatsial'nyye raznovidnosti granitoidov Baytayginskogo massiva (zapadnaya Tuva), Vyssh. Ucheb. Zaved., Izv., Geol. Razved., No. 7, p. 50-61, 1967 (for reference to original Russian paper, see this Bibliog...

Beingessner, D.M.; Spouge, A.R.; Thain, L.M.; Rorabeck, C.H., 1999: Musculoskeletal case 7. Presentation. Large femoral geode associated with osteoarthritis of the hip joint. Canadian Journal of Surgery. Journal Canadien de Chirurgie 42(6): 414, 432-414, 432

Hornby, D.; Slope, D.B.; Gutteridge, R.J.; Sivanesan, A., 1977: Gaeumannomyces cylindrosporus new species a new ascomycete from cereal roots. A new species of Gaeumannomyces, G. cylindrosporus sp. nov., on rotting roots of Triticum and Hordeum is described with Phialophora radicicola var. graminicola as its possible conidial state.

Schwartz, G.F.; Reardon, G., 2004: A cost-effectiveness comparison of bimatoprost versus latanoprost in patients with glaucoma or ocular hypertension. To compare the cost-effectiveness of bimatoprost versus latanoprost for the treatment of glaucoma and ocular hypertension, a cost-effectiveness algorithm was developed to estimate the annual costs and cost per treatment success (cost-effectiveness...

Rasmussen, J.E., 1986: Dermatology potpouri. Pediatrics in Review 8(6): 165-167

Pearson, G.R.; Logan, E.F., 1979: The pathogenesis of enteric colibacillosis in neonatal unsuckled calves. Seven newborn calves were dosed with a known enteropathogenic strain of E. coli O101K?(A) and killed at varying times afterwards. Adhesion of bacteria to the mucosa of the small intestine was observed in all calves. A few organisms were seen in th...

Ponniah, A.; Shakib, S.; Doecke, C.J.; Boyce, M.; Angley, M., 2008: Post-discharge medication reviews for patients with heart failure: a pilot study. Medication misadventure is greatest at times of change such as the transition from hospital to community. Patients with heart failure are prone to medication misadventure due to polypharmacy, inappropriate medication use and frequent readmissions....

Eley R.M., 1991: Post natal growth in the vervet monkey. Ehara, A , Et Al (Ed ) Primatology Today; Xiiith Congress Of The International Primatological Society, Nagoya And Kyoto, Japan, July 18-24, 1990 Xxv+732p Elsevier Science Publishers B V : Amsterdam, Netherlands; (Dist in The Usa And Canada By Elsevier Science Publishing Co , Inc : New York, New York, Usa) Illus Maps 449-450

Reinagel, P.; Reid, R.C., 1998: Visual stimulus statistics and the reliability of spike timing in the LGN. Society for Neuroscience Abstracts 24(1-2): 139