geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

TTP-HUS klinikai kepet utanzo es heveny veseelegtelenseggel szov?d? kronikus DIC hattereben allo metasztatikus prosztatarak patomechanizmus, differencialdiagnozis es kezeles egy eset kapcsan


, : TTP-HUS klinikai kepet utanzo es heveny veseelegtelenseggel szov?d? kronikus DIC hattereben allo metasztatikus prosztatarak patomechanizmus, differencialdiagnozis es kezeles egy eset kapcsan.

A metasztatikus daganatok okozta kr nikus disszemin lt intravaszkul ris koagulop tia (DIC) h tter ben leggyakrabban a hasny lmirigy-, gyomor- s a prosztatar k ll. A trombotikus trombocitop ni s purpura s a hemolitikus ur mi s szindr ma (P-HUS) hasonl klinikai s laborat riumi elt r sei miatt a kr nikus DIC diagn zisa differenci ldiagnosztikai neh zs get jelent. 71 ves f rfi beteg nk k rel?zm ny ben COPD, BPH, szignifik ns carotis-szten zis, gyomorfek ly s alkoholos m jbetegs g szerepel. Szuroksz klet miatti hospitaliz ci ja sor n aktu lisan nem v rz? koagulummal fedett nyomb lfek ly igazol dott. N gy nap m lva akut veseel gtelens g (AVE) miatt ker lt Int zm ny nkbe. A trombocitop nia, a perif ri s v rben fragmentocita, sisaksejtek, a norm lis INR, magas LDH s az AVE felvetette a P-HUS szindr ma gyan j t. T bbsz ri dial zis s plazmaferezis kezel sekben r szes tett k. A talpakon megjelen? trombotikus mikroangiop tia miatt k sz lt alvad si vizsg lat (emelkedett D-dimer, norm lis fibrinog n, a kiss megny lt INR, APTI, norm lis retikulocita- s m rs kelten cs kkent v rlemezkesz m) kr nikus DIC fenn ll s t mutatta. Az emelkedett PSA (19,6 ng/mL) h tter ben a prosztata-adenokarcin ma igazol dott. A csontizot p kiterjedt csont tt teket mutatott. TAB kezel s mellett beteg nk llapota h rom h nap ut n is kiel g t? (PSA 4,6 ng/mL). Tiszt zatlan eredet? trombocitop nia s a norm lis vagy megny lt INR-, APTI- rt kek, emelkedett D-dimer melletti norm lis fibrinog n s retikulocita felfedheti a kr nikus DIC folyamat t. A kr nikus DIC-ben j effektussal alkalmazhat a ter pi s d zis LMWH. A metasztatikus prosztatar k sz v?dm nyek nt kialakult s lyos DIC antiandrog n s nagyd zis ketokonazol kombin ci val kezelhet?. Magyar Onkol gia 54: 351 357, 21.

US$29.90


Other references

Pasztor, E.; Mikita, J.; Gyory, F.; Szakall, S.; Decsy, J.; Peter, M., 1998: Diagnosis of Meckel diverticulum with antegrade small bowel enema. Radiological diagnosis of Meckel diverticulum is a difficult task. Here we report a patient with hereditary sphaerocytosis who complained of a chronic periumbilical pain and in whom antegrade barium enema suggested Meckel diverticulum. The diagnos...

Alpert, J.S., 2013: The team approach--go team!!. American Journal of Medicine 126(4): 275-275

Langston, A.; Casagrande, V.A.; Fox, R., 1986: Spatial resolution of the Galago. The spatial vision of two adult galagos (Galago crassicaudatus) was assessed using a two choice discrimination task to determine their contrast sensitivity. Both contrast sensitivity functions exhibited low and high spatial frequency attenuation w...

Hakala, H.; Mäki, E.; Lönnberg, H., 1998: Detection of oligonucleotide hybridization on a single microparticle by time-resolved fluorometry: quantitation and optimization of a sandwich type assay. Uniformly sized (50 micro m) porous glycidyl methacrylate/ethylene dimethacrylate particles (SINTEF) were used as the solid phase in a sandwich type mixed-phase hybridization assay based on time-resolved fluorescence detection on a single particle...

Gablina I.F., 1991: Mineralogical-geochemical criteria for identifying red-bed formations in metamorphic strata of the Precambrian in connection with copper content. Lithology and Mineral Resources: , Pages 257-269. 1991.

Tanaka, Y.; Aki, T.; Hidaka, Yûki.; Furuya, Yûji.; Kawamoto, S.; Shigeta, S.; Ono, K.; Suzuki, O., 2003: Purification and characterization of a novel fungal alpha-glucosidase from Mortierella alliacea with high starch-hydrolytic activity. The fungal strain Mortierella alliacea YN-15 is an arachidonic acid producer that assimilates soluble starch despite having undetectable alpha-amylase activity. Here, a alpha-glucosidase responsible for the starch hydrolysis was purified from the...

Stephens, R.D.; Feinberg, T., 2006: Managing America's schools in an age of terrorism, war, and civil unrest. When terrorism and natural disasters strike it is extremely important to be able to effectively manage America's schools. From the crises of Columbine, to Red Lake Minnesota, the World Trade Center and Katrina, we are reminded that schools ar...

Roche, M.; Perez-Gimenez, M.E.; Levy, A., 1957: Isotopic tracer method for measurement of iron lost into and re-absorbed from gastro-intestinal bleeding lesions. Nature 180(4597): 1278-1279

Szmygin Milanowska, K.; Kieszko, R.; Chudnicka, A.; Milanowski, J., 2003: Microbial etiologies in community acquired pneumonia (CAP). The objective of this study was to determine the bacterial aetiology, including atypical pathogens, of community-acquired pneumonia (CAP) in adults, and the antibiotic sensitivity of isolated strains. The examined group comprised of 50 patients (2...

Meehan, J.; Ward, C.; Turnbull, A.; Bukowski-Wills, J.; Finch, A.J.; Jarman, E.J.; Xintaropoulou, C.; Martinez-Perez, C.; Gray, M.; Pearson, M.; Mullen, P.; Supuran, C.T.; Carta, F.; Harrison, D.J.; Kunkler, I.H.; Langdon, S.P., 2017: Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells. Hypoxic cancer cells exhibit resistance to many therapies. This study compared the therapeutic effect of targeting the pH regulatory proteins (CAIX, NHE1 and V-ATPase) that permit cancer cells to adapt to hypoxic conditions, using both 2D and 3D c...