geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Antidiabetikus kezeles, mint ujabb lehet?seg a daganatok komplex terapiajaban


, : Antidiabetikus kezeles, mint ujabb lehet?seg a daganatok komplex terapiajaban.

Napjaink modern letform j nak terjed se nemcsak az elh z s, a 2-es t pus diab tesz s a kardiovaszkul ris k rk pek kialakul s nak kedvez, hanem a malignus tumoros betegs gek sz m nak rohamos n veked s vel is j r. Ma m r egyre t bb, els?sorban epidemiol giai jelleg? vizsg lat bizony tja, hogy a 2-es t pus cukorbetegs g s a legt bb daganat kialakul sa k z tt sszef gg s van, melynek oka a k rfolyamatok k z s r szleteiben keresend?. Az egyik ilyen r szlet a szervezet kezdeti hyperinsulinaemi val s k sei hyperglycaemi val k s rt inzulinrezisztens llapot nak l trej tte. Ezt daganatos betegekben a tumorsz vet fokozott inzulin rz kenys ge s gl k zfelv tele eg sz ti ki. A tumoros szervezetben teh t a daganat sz m ra el?ny s, a 2-es t pus diab teszre jellemz? sz nhidr t-anyagcserezavar alakul ki. Ennek megfelel?en logikusnak t?nik or lis inzulinszenzitiz l antidiabetikumok alkalmaz si lehet?s g nek felvet se tumorellenes indik ci ban is. Az irodalmi adatok t lnyom r sze al t masztja ezt az elgondol st, mind a biguanid t pus metformin, mind a tiazolidindionok (TZD) eset ben. Kedvez?ek az el?zetes eredm nyek az inzulinszer? n veked si faktor receptor (IGFR) elleni monoklon lis antitest-k sz tm nyek daganatellenes alkalmaz s nak ter n is. A cukorbetegs g s a malignus tumorok komplex anyagcserekontroll r szek nt t rt n?, egy ttes kezel se teh t jabb lehet?s geket adhat az onkol giai ter pi k k r ben, melyek r v n nemcsak a szervezetet er?s tj k a tumor ellen ben, hanem a daganatot is gyeng tj k a szervezet v delm ben. Magyar Onkol gia 54: 315 323, 21.

US$29.90


Other references

Muszynski, Z., 1967: Mechanization of loading long logs at log depots. Gives time studies of loading Beech, Spruce and Fir logs (0.2-1.8 cu.m.) on to railway wagons by self-propelled crane and by hand winch.

Hayes, R.L.; Roth, D., 1973: Acridine binding of buccal cells and "field alteration" associated with oral cancer: a review. Oral Surgery, Oral Medicine, and Oral Pathology 36(4): 517-532

Waßmuth, R., 2015: Endorsement of risk management and patient safety by certification of conformity in health care quality assessment. Certification of conformity in health care should provide assurance of compliance with quality standards. This also includes risk management and patient safety. Based on a comprehensive definition of quality, beneficial effects on the management o...

Chiumello, D.; Cavaliere, F.; D.C.smo, G.; Pietrini, D.; Capogna, G., 2012: A year in review in Minerva Anestesiologica 2011. Minerva Anestesiologica 78(2): 265-280

Herneth, A.M.; Steindl, P.; Ferenci, P.; Roth, E.; Hörtnagl, H., 1998: Role of tryptophan in the elevated serotonin-turnover in hepatic encephalopathy. The increase of the brain levels of 5-hydroxyindoleacetic acid (5-HIAA) in hepatic encephalopathy (HE) suggests an increased turnover of serotonin (5-HT). To study the role of tryptophan on the increased brain 5-HT metabolism in HE, we attempted t...

Toll, Ed., 1889: Ueber das Vorkommen von Foraminiferen in Silur der neusibirischen Insel Kotelny. JB Mineral, 203 & 204

Bolto B.A., 1987: Water treatment technology. Pages 191-201 1987

DesAutels David, 1993: Thrust structure in Michigan could point toward more targets. Oil and Gas Journal 91(33): 86-88

Peterka, H.; Budahn, H.; Schrader, O.; Havey, J., 2003: Transfer of a male-sterility-inducing cytoplasm from onion to leek ( Allium ampeloprasum). Two interspecific triploid (AAC) hybrids (84/1-94 and 99/1-94) from crosses between onion [ Allium cepa (2 n=2 x=16, CC)] and leek [ A. ampeloprasum (2 n=4 x=32, AAAA)] were backcrossed to leek in order to transfer a male-sterility-inducing cytopl...

Buntain, B.J.; Selman, I.E., 1980: Controlled studies of various treatments for neonatal calf diarrhoea in calves of known immunoglobulin levels. The effects of whole blood transfusions (trial 1), balanced fluid replacement therapy (trial 2) and fluids plus antibiotics (trial 3) on spontaneously occurring diarrhoea were studied under controlled experimental situations using newborn calves o...