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Paradigmavaltas a tud?rakok nem sebeszi mintaveteleben

, : Paradigmavaltas a tud?rakok nem sebeszi mintaveteleben.

A nem-kissejtes t d?r kok sz vettani alcsoportjai elt r? prognosztikai tulajdons gokkal s ter pi s rz kenys ggel rendelkeznek. Az egy nre szabott kezel sek c lpontjainak azonos t sa a hagyom nyos patol giai vizsg latok mellett j m dszerek bevezet s t ig nyli. Az alcsoportok elk l n t s nek s a c lpontok kijel l s nek m dszereit seb szi biopszi s anyagon dolgozt k ki (erre a t d?r kos esetek 2%- ban van lehet?s g). A t d?daganatok t bbs ge felfedez skor m r nem oper lhat , gy a diagn zisok t bbs ge l nyegesen kisebb, bronchoszk pos, t?biopszi s mint kon, de d nt?en citol giai keneteken alapul. A korl tozott nagys g mint kb l a korrekt kezel sek rdek ben azonban egyre t bb immunmorfol giai s molekul ris patol giai vizsg latot sz ks ges elv gezni. E szeml letv lt s miatt a t d?biopszi t v gz? szakemberek mintav teli technik j nak s lypontj t meghat roz an a sz vettani feldolgoz sra alkalmas m dszerek fel kell thelyezni. A t bbf le biopszi s technika kombin l sa (sz vettan/citol gia, illetve h rg?kefe, BAL, TBNA stb.), a citol giai mint k sejtblokkokba gyaz sa, valamint immunhisztok miai s molekul ris patol giai vizsg latokra felk sz lt patol giai laborat rium biztos thatja a t d?r kok megfelel? diagn zis t s a betegek individualiz lt kezel s t. Magyar Onkol gia 54: 297 31, 21.


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