geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A multi-institution evaluation of deformable image registration algorithms for automatic organ delineation in adaptive head and neck radiotherapy


, : A multi-institution evaluation of deformable image registration algorithms for automatic organ delineation in adaptive head and neck radiotherapy. Radiation Oncology 7: 90-90

Adaptive Radiotherapy aims to identify anatomical deviations during a radiotherapy course and modify the treatment plan to maintain treatment objectives. This requires regions of interest (ROIs) to be defined using the most recent imaging data. This study investigates the clinical utility of using deformable image registration (DIR) to automatically propagate ROIs. Target (GTV) and organ-at-risk (OAR) ROIs were non-rigidly propagated from a planning CT scan to a per-treatment CT scan for 22 patients. Propagated ROIs were quantitatively compared with expert physician-drawn ROIs on the per-treatment scan using Dice scores and mean slicewise Hausdorff distances, and center of mass distances for GTVs. The propagated ROIs were qualitatively examined by experts and scored based on their clinical utility. Good agreement between the DIR-propagated ROIs and expert-drawn ROIs was observed based on the metrics used. 94% of all ROIs generated using DIR were scored as being clinically useful, requiring minimal or no edits. However, 27% (12/44) of the GTVs required major edits.DIR was successfully used on 22 patients to propagate target and OAR structures for ART with good anatomical agreement for OARs. It is recommended that propagated target structures be thoroughly reviewed by the treating physician.

US$19.90

PMID: 22704464

DOI: 10.1186/1748-717X-7-90


Other references

Serva L., 1990: Role of Earth sciences in the safety analysis of the site of a particular typology of an industrial plant; the reference earthquake at Viadana. Bollettino della Societa Geologica Italiana 109(2): 375-411

Xie, J.; Li, C.; Zhou, Q.; Wang, W.; Hou, Y.; Zhang, B.; Wang, X., 2012: Large improvement in the catalytic activity due to small changes in the diimine ligands: new mechanistic insight into the dirhodium(II,II) complex-based photocatalytic H2 production. Two dirhodium(II) complexes, [Rh(II)(2)(μ-O(2)CCH(3))(2)(bpy)(2)](O(2)CCH(3))(2) (Rh(2)bpy(2); bpy = 2,2'-bipyridine) and [Rh(II)(2)(μ-O(2)CCH(3))(2)(phen)(2)](O(2)CCH(3))(2) (Rh(2)phen(2); phen = 1,10-phenanthroline) were synthesized, and...

Holton, A.; Love, B., 2014: Lonely no more: remembering text messaging in mHealth conversations. Health Communication 28(5): 530-532

Martell, M.; Aldasoro, A., 1972: Detection of virus rabies. Boletin de la Oficina Sanitaria Panamericana. Pan American Sanitary Bureau 73(2): 117-123

Kalashnikov, A.M.sik, A., 1980: Scientific bases for increasing meat production and improving its quality. Zhivotnovodstvo (8) 5-8

Faghihi Langroudi, T.; Shabestari, A.Arjmand.; Pourghorban, R.; Pourghorban, R., 2015: Idiopathic inferior mesenteric arteriovenous fistula: a rare cause of pulsatile abdominal mass. Inferior mesenteric arteriovenous fistula (AVF) is an extremely rare vascular abnormality which may be idiopathic or secondary to previous trauma or surgery, and it may result in portal hypertension or ischemic colitis if left untreated. Imaging c...

Vekemans, M.J.; Trasler, T., 1985: A preliminary compilation of cytogenetic studies and of cultured cells derived from individuals homozygous or heterozygous for ataxia-telangiectasia. Kroc Foundation Series 19: 205-214

Aslan, V.; Maden, M.; Erganis, O.; Birdane, F.M.; Corlu, M., 2002: Clinical efficacy of florfenicol in the treatment of calf respiratory tract infections. A study on the aetiology of calf pneumonia and the clinical efficacy of florfenicol, a new antibiotic in Turkey, is presented. 27 weaned and unweaned calves (13 males and 14 females) between one and 16 months of age brought to the clinic of the Se...

Spyracopoulos, L.; Yee, A.A.; O'neil, J.D.J., 1996: Backbone dynamics of an alamethicin in methanol and aqueous detergent solution determined by heteronuclear 1H-15N NMR spectroscopy. The (15)N relaxation rates of the α-aminoisobutyric acid (Aib)-rich peptide alamethicin dissolved in methanol at 27°C and 5°C, and dissolved in aqueous sodium dodecylsulfate (SDS) at 27°C, were measured using inverse-detected one-and two-dimen...

Mathur, O.P.; Mathur, S.K.; Talati, N.R., 1983: The effect of leaching with various soil amendments on soil properties and on grain yields of paddy in salt affected soils. Paddy rice was grown on salt-affected soil treated with 2.5, 5 or 7.5 t CaCl2 2.5, 7.5 or 15 t gypsum and 25, 50 or 75 t FYM/ha. 100 kg N and 30 kg P2O5/ha was applied to all plots; half the N and all the phosphate were added as a basal dressing,...