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Estudio comparativo sobre la eficacia de los tratamientos de intervencion cognitiva entre pacientes con deterioro cognitivo secundario a daño neurologico focal y a patología neurodegenerativa


, : Estudio comparativo sobre la eficacia de los tratamientos de intervencion cognitiva entre pacientes con deterioro cognitivo secundario a daño neurologico focal y a patología neurodegenerativa.

Se ha publicado que los tratamientos de Intervenci n Cognitiva (IC) resultan eficaces en pacientes con deterioro secundario a da o neurol gico focal (DNF), no sucediendo lo mismo en pacientes con enfermedades neurodegenerativas (EN). Estudiar la efectividad de los tratamientos de IC comparando los resultados entre pacientes con DNF y EN. Dise o/m todos Se seleccionaron para el screening un total de 144 pacientes, que fueron divididos en 3 grupos: DNF (G1), EN (G2) y causas mixtas (G3). En G1 se incluyeron particularmente pacientes con secuelas cognitivas postraumatismo de cr neo y accidente cerebrovascular. En G2 se incluyeron pacientes con demencias y deterioro cognitivo leve de etiolog a degenerativa. Los grupos fueron pareados seg n edad/escolaridad. Se compararon variables cognitivas, conductuales, funcionales y calidad de vida al inicio y al final del tratamiento. Con posterioridad al tratamiento se encontraron diferencias significativas entre los grupos en algunos aspectos de calidad de vida y memoria subjetiva. Con respecto a la evoluci n en G1 (n=43) se produjeron mejor as en actividades b sicas (-1,55; p=,4) e instrumentales (AIVD) (-1,63; p = ,7) de la vida diaria, escala de memoria subjetiva (13,36; p = ,2) e inventario neuropsiqui trico (7,73; p = ,3). En G2 (n=34) se encontr una tendencia en mejorar AIVD (-1,3; p = ,8) y aspectos de calidad de vida (-1,591; p = ,6). En G3 (n=12) no se evidenciaron cambios significativos. En nuestra muestra la IC produjo mejor as significativas en algunos aspectos cognitivos, conductuales, funcionales y de calidad de vida. El beneficio fue mayor en pacientes con DNF. Este trabajo representa los resultados preliminares de un estudio a mayor escala poblacional. Introduction In recent years, an increasing number of studies published assessing the effectiveness of CT programs in patients with ABD have shown that these therapies may have bene?cial effects on cognitive and functional measures. On the other hand, the efficacy of these type of treatment in patients with ND is still under debate. To evaluate and compare the effectiveness of a Cognitive Training (CT) program in patients with Acquired Brain Damage (ABD) and neurodegenerative diseases (ND). Design/Methods 144 patients were assessed with neuropsychological, neurological, neuropsychiatry and functional assessments. The sample was divided in three groups: ABD (G1), ND (G2) and mixed disorders (G3). G1 included mainly patients with Traumatic Brain injury and Stroke. G2 included patients with degenerative dementias and mild cognitive impairment. Groups were matched for age, education and number of CT sessions. The effects on cognition, behavioral, functional and quality of life (QOL) were considered as the primary outcome measures, and evaluated at the beginning and at the end of the CT program. Within G1 patients (n=43) an improvement was found in patient's basic (-1.55;p.4) and instrumental (-1.63;p.7) activities of daily living (ADL) scores.

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