geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

An unexpected promiscuous activity of 4-oxalocrotonate tautomerase: the cis-trans isomerisation of nitrostyrene


, : An unexpected promiscuous activity of 4-oxalocrotonate tautomerase: the cis-trans isomerisation of nitrostyrene. Chembiochem 13(13): 1869-1873

Serendipitous switch: While exploring cis-nitrostyrene as a potential electrophile in Michael-type addition reactions catalysed by the enzyme 4-oxalocrotonate tautomerase (4-OT), it was unexpectedly found that 4-OT catalyses the isomerisation of cis-nitrostyrene to trans-nitrostyrene (k(cat) /K(m) = 1.9×10(3)  M(-1)  s(-1) ).

US$19.90

PMID: 22851288

DOI: 10.1002/cbic.201200371


Other references

Shapiro, A.M., 1968: First additions to 'Butterflies of the Delaware Valley'. Entomological News, 79: 150-152

Chamberlain, A.C.; Turner, F.M.; Williams, E.K., 1952: The evaluation of white-cell counting in radiation protection. British Journal of Radiology 25(292): 169-176

Mccall R.D., 1985: Genetic influences on forced exercise endurance differences between c 57bl 6 and balb cby mice maintained at sea level and in chronic hypoxic hypoxia. Genetics 110(3 PART 2): S33

Chen-An-Lei; Wang-Kai-Rong; Me-Xiao-Li; Liu-Ying-Xin, 2007: Responses of microbial biomass P to the changes of organic C and P in paddy soils under different fertilization systems. Based on a fifteen years field experiment in double rice-cropping region of subtropical China, the responses of microbial biomass P (MB-P) to organic C and P in red paddy soils under different fertilization systems were investigated. The results i...

Hack, H.R.B., 1963: Tomato seed germination & emergence at controlled soil-moisture tensions from 0.5 to 20cm mercury. Germination was slow & poor in the wetter treatments at 0.5 & 1 cm Hg & satisfactory at 2cm. Seedlings appeared more rapidly at 2 cm than at 20cm Hg.

Bian Lizeng; Zhang Shuichang; Zhang Baomin; Mao Shaozhi; Yin Leiming, 2001: A kind of coccoid dinoflagellates-like fossils gives a new explanation of source of dinosterane in the Early-Middle Cambrian. The coccoid fossils covered with thick gelatinous envelope containing several gametes are discovered in gypsum and salt deposits of Cambrian, H (sub 4) well and chert bed of the base of Yuertus Formation (epsilon (super 1) (sub 1) ) of Xiaoerbulak...

Heuckendorff, M.; Jensen, H.H., 2017: Removal of some common glycosylation by-products during reaction work-up. With the aim of improving the general glycosylation protocol to facilitate easy product isolation it was shown that amide by-products from glycosylation with trichloroacetimidate and N-phenyl trifluoroacetimidate donors could be removed during rea...

Briggs, R.; Leonard, W.A., 1977: Mortality and ecological structure: a canonical approach. Social Science & Medicine 11(14-16): 757-762

Anonymous, 2012: Epigenetic Alteration of PGP95 in Human Prostate Cancer. The expression level of protein G product 9.5 (PGP9.5) is downregulated because of promoter CpG hypermethylation in several tumors. We speculated that impaired regulation of PGP9.5 through epigenetic pathways is associated with the pathogenesis of...

Lithoxoidou, A.T.; Bakalbassis, E.G., 2006: PCM study of the solvent and substituent effects on the conformers, intramolecular hydrogen bonds and bond dissociation enthalpies of 2-substituted phenols. A PCM continuum model, at the DFT/B3LYP level, is used to study the solvent and substituent effects on the conformers, intramolecular hydrogen bond (HB) enthalpies, (Delta H(intra)s), and O-H bond dissociation enthalpies, (BDEs), in 2-substituted...