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Nationwide survey of acromegaly in South Korea

, : Nationwide survey of acromegaly in South Korea. Clinical Endocrinology 78(4): 577-585

It was previously reported in Korea that there were 1.4 case per million per year of acromogly. This was low in comparison to the extrapolated values of western European countries. We expected that the incidence of acromegaly would be much higher now due to recently improved medical facilities, diagnostic tools, and coverage of medical insurance to all the population of South Korea. The purpose of this nationwide survey was to examine the incidence and prevalence of acromegaly patients, mode of treatment, and outcome of surgical treatment of recent 5 years. and patientsWe requested and collected the medical records of all possible acromegaly patients from 74 secondary or tertiary medical institutes in Korea from 2003 to 2007 retrospectively. Date of diagnosis and treatment, tumor size, pre- and postoperative hormonal level, treatment modality and usage of medication were collected. During 5 years, 1350 acromegaly patients had been registered. The average annual incidence was 3.9 cases per million during this period, and prevalence had increased up to 27.9 cases per million in 2007. Male:female ratio was 1:1.2, and mean age at diagnosis was 44.1 years. Macroadenoma was dominant (82.9%). Transsphenoidal adenoidectomy was used the most as primary treatment (90.4%). This Korean acromegaly survey offers a realistic overview of the predominant epidemiological characteristics of acromegaly in Korea. Annual incidence was at a similar level with western countries. Efforts to diagnose and control the disease earlier are recommended.


PMID: 22909047

DOI: 10.1111/cen.12020

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