geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

A case of cholangiolocellular carcinoma in which intrahepatic cholangiocarcinoma was confirmed from appearance to development


, : A case of cholangiolocellular carcinoma in which intrahepatic cholangiocarcinoma was confirmed from appearance to development. International Cancer Conference Journal 2(1): 45-50

We describe the case of a 68-year-old asymptomatic woman with cholangiolocellular carcinoma (CoCC) combined with intrahepatic cholangiocarcinoma (ICC). She was diagnosed with hepatic hemangioma and followed up for approximately three years. Because the hepatic tumor increased in size and was clinically diagnosed as ICC without metastasis, a hepatectomy was performed. Histopathological examination confirmed that the tumor was CoCC surrounded by a region of ICC. Analysis of the computed tomography images from the two years before the operation confirmed that the ICC arose from a part of the preexisting CoCC and increased over a short period of time. Three months after the operation, cancer recurred in the liver and regional lymph nodes; therefore, we performed chemotherapy for one year and four months, followed by hepatectomy and dissection of the lymph nodes. Microscopic findings showed that the hepatic recurrence was CoCC, and that all of the malignant lymph nodes were metastases from ICC. This is a suggestive and valuable case that informs us of the transformation process from CoCC to ICC; it indicates that ICC differentiated from CoCC and adopts a different manner of metastasis from the original mother CoCC.

US$19.90

DOI: 10.1007/s13691-012-0062-x


Other references

Alarcón, M.Antonio.; Diaz, K.Tatiana.; Aranda, L.; Cafferata, E.Alfredo.; Faggion, C.Mariano.; Monje, A., 2016: Use of Biologic Agents to Promote Bone Formation in Implant Dentistry: A Critical Assessment of Systematic Reviews. The use of biologic agents is emerging in bone regeneration procedures due to their ability to increase cellular events in wound healing and therefore to obtain more predictable outcomes. Hence, the aim of the present study was to critically evalu...

Schneider H G.; Knieknecht G., 1986: Formation of dental plaque in relation to food ingestion. The formation of dental plaque during the consumption of hard, normal and soft diet was examined on 100 children (4-6 years old) per diet group. No tooth-brushing was done during the test for two days. The average of plaque-index (by QUIGLEY and H...

Efremov A.A., 1974: Soviet investigations on the north sea whiting stock in 1972. Annales Biologiques (Copenhagen) 29(1972): 99

Saha M.; Khan E., 1989: Effect of different fixatives and processing techniques on morphometrics of pratylenchus zeae graham 1951. Effects of various techniques in combination (killing, fixing and processing) for preparing permanent mounts of nematodes on morphometrics using 4% Formalin, TAF, FAA and Formalin + Glycerine and two processing methods and glycerol-ethanol (Seinho...

Anonymous, 2016: Safety net hospital, community providers collaborate to improve transitions. A Care Transitional Task Force at San Francisco General Hospital created a cross-continuum program that has reduced readmissions and increased timely primary care visits for discharged patients. A basic bundle of services includes communication be...

Dugdale, A.E.; Muller, M.; Alsop Shields, L., 1994: Patterns of weight growth in aboriginal children on Queensland communities. We have used data from existing health records to study the birth weights and percentage weights for age (%W/A) of children in five Aboriginal communities in Queensland. The data are from cohorts of children born in the 1950s-80s at Cherbourg, the...

Anonymous, 2013: Guía practica de diagnostico y tratamiento de la acromegalia. La acromegalia y el gigantismo se deben a la producci n excesiva de GH, generalmente por un adenoma hipofisario. Es una enfermedad poco frecuente. El diagn stico se realiza ante un paciente con un cuadro cl nico sugerente con la demostraci n de co...

Semenov, A.G.; Tamm, N.N.; Apple, F.S.; Schulz, K.M.; Love, S.A.; Ler, R.; Feygina, E.E.; Katrukha, A.G., 2016: Searching for a BNP standard: Glycosylated proBNP as a common calibrator enables improved comparability of commercial BNP immunoassays. Circulating B-type natriuretic peptide (BNP) is widely accepted as a diagnostic and risk assessment biomarker of cardiac function. Studies suggest that there are significant differences in measured concentrations among different commercial BNP imm...

Schwartz, L.H.; Marcus, R.; Condon, R., 1978: Multidisciplinary group therapy for rheumatoid arthritis. Psychosomatics 19(5): 289-293

Marti, S.; Baloh, R.W.; Jen, J.C.; Straumann, D.; Jung, H.H., 2008: Progressive cerebellar ataxia with variable episodic symptoms--phenotypic diversity of R1668W CACNA1A mutation. We describe a family with an R1668W mutation in the CACNA1A gene who presented with a broader clinical spectrum and more variable features than previously reported. The mother had a pure progressive cerebellar ataxia of late onset with downbeat n...