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Impact of Black T Supra on Haematology of Albino Rats

, : Impact of Black T Supra on Haematology of Albino Rats.

The toxic haematological effects of carpet dye Black T Supra on various hematological parameters were evaluated in Rattus norvegicus (Berkenhout) following oral exposure at sublethal dose of this dye (20 mg/kg of body weight per day) for different periods. Exposure to this dye decreased haemoglobin content from 17 to 12.6 percentage, RBC from 6.5 to 2.88 x 106 per cmm., PCV from 54 to 34.5 percentage at the end of 90 days, HCV from 83.07 to76.10 c.(i. at the end of 30 days and MCHC after 90 days from 31.48 to 23.33 as compared to control. However, an increase was observed in MCV from 83.07 to 187.5 c.(i. after 30 days up to 120 days, MCHC from 31.48 to 37.10 percentage up to 90 days and MCH from 26.15 to 43.75 pg. PCV become constant after 90 days. Leukocyte count increases up to 90 days from 10.0 x 103 per cmm to 16.28 x 103 per cmm and decreased to 6.65 x 103 per cmm after 120 days. This caused haemocytic anemia, leucopenia, monocytosis, neutropenia showing declined immunity. The hyp.


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