+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Detecting single photons: a supramolecular matter?

, : Detecting single photons: a supramolecular matter?. Febs Letters 587(1): 1-4

Rod photoreceptors detect single photons through a tradeoff of light collecting ability, amplification and speed. Key roles are played by rhodopsin (Rh) and transducin (G t ), whose complex supramolecular organization in outer segment disks begs for a functional interpretation. Here we review past and recent evidence of a temperature-dependence of photon detection by mammalian rods, and link this phenomenon with the putative oligomeric organization of Rh and new ideas on the dynamics of Rh G t interaction. Identifying an electrophysiological correlate of the supramolecular organization of Rh and G t may shed light on the evolutionary advantage it confers to night vision. Rhodopsin has been reported to natively dimerize and oligomerize in rod disks. This poses conceptual challenges to the classical model of phototransduction. We present neglected data on the effect of temperature on single photon signaling. This data may link rod function to the supramolecular organization of rhodopsin.


PMID: 23178927

DOI: 10.1016/j.febslet.2012.11.015

Other references

Kinosita, H.; Dryl, S.; Naitoh, Y., 1964: Spontaneous change in membrane potential of Paramecium caudatum induced by barium and calcium ions. Bulletin de l'Academie Polonaise des Sciences Sci Biol, 12: 459-461

Pereira, R.; Hitzeroth, I.I.; Rybicki, E.P., 2009: Insights into the role and function of L2, the minor capsid protein of papillomaviruses. Human papillomaviruses (HPV) are responsible for the most common human sexually transmitted viral infections, and high-risk types are responsible for causing cervical and other cancers. The minor capsid protein L2 of HPV plays important roles in v...

Suedkamp, M.; Geissler, H.J.; Hoezl, P.; De-Vivie, E.R., 2000: Risikostratifizierung in der herzchirurgie: Entscheidungshilfe bei der Indikationsstellung. Various risk scores have been developed for the assessment of operative risk in cardiac surgery. Although risk stratification has been acknowledged as a useful tool to analyze trends in therapy and changes in patients populations, its relevance in...

Tsuru S., 1970: Proceedings of international symposium environmental disruption. Proceedings Of International Symposium Environmental Disruption 348

Fogue, M.; Garrido, P.; Martinez, F.J.; Cano, J-Carlos.; Calafate, C.T.; Manzoni, P., 2013: Identifying the key factors affecting warning message dissemination in VANET real urban scenarios. In recent years, new architectures and technologies have been proposed for Vehicular Ad Hoc networks (VANETs). Due to the cost and complexity of deploying such networks, most of these proposals rely on simulation. However, we find that most of the...

Friedman, E.A., 1985: Improving the course of diabetic nephropathy. Contributions to Nephrology 44: 173-193

Brockman, R., 1990: Medication and transference in psychoanalytically oriented psychotherapy of the borderline patient. The regressive potential of the borderline patient has been recognized ever since the term was first introduced by Adolph Stern in 1938. He believed these patients were "too ill for classical psychoanalysis," and indeed almost all who ha...

Yamada, A.; Tanno, K., 1993: Effect of glycyrrhizin on the damage to the pancreas caused by DL-ethionine in rats: Light microscopic observation. DL-ethionine causes acute or chronic pancreatitis (Naito, 1958; Nagata et al., 1981). In the present study, rats were maintained on a choline-deficient, low-protein diet. When the rats were given Dl-ethionine alone intraabdominaly, the pancreas ce...

Gilliss, C.L.; Kulkin, I.L., 1991: Monitoring nursing interventions and data collection in a randomized clinical trial. Western Journal of Nursing Research 13(3): 416-422

Varró, V., 1981: Dysfunction of Oddi's sphincter, a problem diagnosis. Problems of the diagnosis of Oddi's sphincter dysfunction are discussed based on experiences gained mostly in cholecystectomized patients. In every case the existence of an organic lesion interfering with free bile flow was ruled out. The fun...