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ICU outcomes in cystic fibrosis following invasive ventilation


, : ICU outcomes in cystic fibrosis following invasive ventilation. Respirology 18(4): 585-586

Cystic fibrosis (CF) is the most common lethal genetic disorder in Caucasians, affecting more than 3,600 people in Australia and New Zealand, and more than 70,000 globally. Most of the morbidity and mortality relates to chronic airway infection commencing in early infancy and death usually occurs from respiratory failure (1, 2). Survival has improved dramatically over the past 30 years with institution of multidisciplinary CF care teams, introduction of newborn screening to allow early intervention, aggressive nutritional support and effective antibiotic treatments and is now predicted to be 50 years in those born with CF from the 1990's onwards . An important and relatively new development is that adults with CF are now living for much longer with established severe lung disease , which makes the timing of lung transplantation more difficult to determine. Acute complications in patients with minimal respiratory reserve present healthcare teams with major decision-making challenges especially for invasive ventilatory support in the Intensive Care Unit.

US$19.90

PMID: 23461647

DOI: 10.1111/resp.12077


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