+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Síndrome compartimental abdominal y síndrome de distres intestinal agudo

, : Síndrome compartimental abdominal y síndrome de distres intestinal agudo.

La Hipertensi n Intraabdominal (HIA) y el S ndrome Compartimental Abdominal (SCA) son entidades frecuentes en los pacientes graves y cursan con una alta mortalidad. En esta revisi n se actualizan los aspectos m s debatidos sobre la HIA y el SCA: factores desencadenantes, epidemiolog a, pron stico, m todos de medici n de la presi n intraabdominal (PIA), consecuencias fisiopatol gicas y medidas terap uticas, tanto m dicas como quir rgicas. Se plantea que, simult neamente a los mecanismos de lesi n estrictamente f sicos, como la compresi n directa de vasos y rganos intraabdominales, la transmisi n de la PIA a otros compartimentos y el descenso del gasto card aco, pueden intervenir tambi n una serie de mediadores inmunoinflamatorios generados en el propio intestino. La hipoperfusi n, la isquemia mantenida y el fen meno isquemia-reperfusi n actuar an sobre la microbiota, el epitelio y sistema inmune intestinal desencadenando el S ndrome de Distr s Intestinal Agudo, una respuesta inflamatoria sist mica y una eventual disfunci n multiorg nica que pueden aparecer en fases tard as del SCA. Seriously ill patients frequently present intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) as complications, and the associated mortality is very high. This review offers an update on the most controversial aspects of these entities: factors favoring their appearance, the most common causes, prognosis, and methods of measuring intra-abdominal pressure (IAP), physiopathological consequences in relation to the different organs and systems, and the currently accepted treatment measures (medical and/or surgical). Simultaneously to the strictly physical mechanisms of injury, such as direct compression of intra-abdominal organs and vessels, the transmission of IAP to other compartments, and the drop in cardiac output, a series of immune-inflammatory mediators generated in the intestine itself may also intervene. Hypoperfusion, sustained ischemia and the ischemia-reperfusion phenomenon, would act upon the microbiota, intestinal epithelium and intestinal immune system, triggering a systemic inflammatory response and multiorgan dysfunction that appears in the final stages of ACS.


Other references

Fairchild, G.B., 1939: Notes on the genus Acanthocera Macquart (Dipt. Tabanidae). Revista de Entomologia Rio de Janeiro, 10: 14-27

Harris, B., 2002: Child murders in Central America. Lancet 360(9344): 1508-1508

López Miranda, J.; Pérez Jiménez, F.; Fernández-Puebla Giménez, R.; Torre-Cisneros, J.; Hidalgo Rojas, L.; Jiménez Perepérez, J.A., 1990: Level of knowledge among medical students about hypercholesterolemia. The general practitioner plays a fundamental role in the control of hypercholesterolemia as a risk factor of atherosclerosis; therefore, education about this issue should be an important part of the undergraduate curriculum. Thus, we carried out t...

Acciari, V.A.; Torresi, M.; Migliorati, G.; D.G.annatale, E.; Semprini, P.; Prencipe, V., 2011: Characterisation of Listeria monocytogenes strains isolated from soft and semi-soft cheeses sampled in a region of Italy. A total of 47 Listeria monocytogenes strains isolated in a survey of cheeses sampled from retail outlets were characterised. Five cheeses (Gorgonzola, Taleggio, Asiago, Crescenza and Brie) were chosen from the most popular soft and semi-soft chees...

Anonymous, 2011: A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cellsin vitro, and testosterone decrease at lower levels. The major herbicide used worldwide, Roundup, is a glyphosate-based pesticide with adjuvants. Glyphosate, its active ingredient in plants and its main metabolite (AMPA) are among the first contaminants of surface waters. Roundup is being used incre...

Joseph, T.; Wooden, R.; Bryant, A.; Zhong, M.; Lu, Z.; Foster, D.A., 2001: Transformation of cells overexpressing a tyrosine kinase by phospholipase D1 and D2. Phospholipase D (PLD) activity is elevated in response to most mitogenic signals. Two mammalian PLD genes (PLD1 and PLD2) have been cloned and their gene products have been characterized. PLD1 is a downstream target of the Ras/RalA GTPase cascade...

Day R., 1993: Geological Survey of Queensland. 125th anniversary. History of the Queensland Geological Survey and its fossil collections since the Survey's formation - an edited version of the author's detailed research document.

Nofsinger, Y.C.; Tom, L.W.; LaRossa, D.; Wetmore, R.F.; Handler, S.D., 1997: Periauricular cysts and sinuses. Periauricular cysts, sinuses, and fistulas occur commonly in the pediatric population. They arise from developmental defects of the first branchial cleft and first branchial arch. In most instances the diagnosis and management of these conditions...

Nechiporenko, Na, 1977: Moscow branch of the All Union Research Institute of Plant Industry for the non Chernozem Zone. Biulleten' 1 9-15

Kornhuber, J.; Parsons, C.G.; Hartmann, S.; Retz, W.; Kamolz, S.; Thome, J.; Riederer, P., 1995: Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: Binding and patch clamp studies. Orphenadrine has been used as an antiparkinsonian, antispastic and analgesic drug for many years. Here we show that orphenadrine inhibits [3H]MK-801 binding to the phencyclidine (PCP) binding site of the N-methyl-D-aspartate (NMDA)-receptor in hom...