geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of rumen-protected γ-aminobutyric acid on feed intake, lactation performance, and antioxidative status in early lactating dairy cows


, : Effects of rumen-protected γ-aminobutyric acid on feed intake, lactation performance, and antioxidative status in early lactating dairy cows. Journal of Dairy Science 96(5): 3222-3227

The objective of this study was to investigate effects of rumen-protected γ-aminobutyric acid (GABA) on dry matter intake, milk performance, and serum metabolites in Chinese Holstein lactating cows. Thirty-nine multiparous cows were blocked based on days in milk (60 ± 6.3 d; mean ± SD) and milk production (30.9 ± 4.17 kg; mean ± SD), and were randomly assigned to 1 of 4 treatments, with rumen-protected GABA added at levels of 0, 0.8, 1.6, or 2.4 g/d, the actual predicted available amounts being 0, 0.30, 0.61, or 0.91 g of GABA/d, respectively. The experiment lasted for 8 wk, with the first week for adaptation. Milk yield and milk compositions were recorded weekly, and serum concentrations of GABA, neuropeptide Y, and biochemical and antioxidant variables were analyzed in the first, fourth, and seventh weeks of the study. Dry matter intake linearly increased in cows receiving added GABA compared with that for the control. Addition of 0.8 g of GABA/d was associated with higher milk yield than the other treatments, but contents of milk protein and fat did not differ across the treatments. Dietary GABA tended to quadratically enhance the serum content of GABA (23.6, 30.2, 29.8, or 28.3 mmol/L for 0, 0.8, 1.6, or 2.4 g/d, respectively), and increased neuropeptide Y, with the highest value (3.07 ng/L) for 0.8 g of GABA/d. Nonesterified fatty acid quadratically decreased with GABA addition, with the lowest value (218.1 μmol/L) for 0.8 g of GABA/d. Serum glutathione peroxidase and superoxide dismutase quadratically increased in cows fed GABA, whereas serum malondialdehyde was quadratically reduced for all GABA groups. Rumen-protected GABA quadratically improved N efficiency across all treatments, contributing to the enhanced production of milk and milk protein and reduced N emission to the environment. In conclusion, addition of rumen-protected GABA is beneficial for early lactation dairy cows in terms of feed intake, lactation performance, and animal health.

US$19.90

PMID: 23498023

DOI: 10.3168/jds.2012-6285


Other references

Jordan William M., 1983: Canals of the Lebanon Valley. Pennsylvania Geology 14(2): 2

Dexter T.M., 1987: Growth factors involved in hemopoiesis. Journal of Cell Science 88(1): 1-16

Taimi, M.; Defacque, H.; Commes, T.; Favero, J.; Caron, E.; Marti, J.; Dornand, J., 1993: Effect of retinoic acid and vitamin D on the expression of interleukin-1 beta, tumour necrosis factor-alpha and interleukin-6 in the human monocytic cell line U937. We have previously described a synergism between the two physiological hormones, retinoic acid (RA) and 1 alpha,25-dihydroxyvitamin D3 (VD) in the induction of U937 cell differentiation towards a more mature state. Herein, we investigated the regu...

Malhotra, V.V.; Khehra, A.S.; Dhillon, B.S., 1986: Variability in resistance of local maize germplasm to brown-stripe downy-mildew and its relationship with rainfall in the areas of their adaptation. Analysis of data on resistance to Sclerophthora rayssiae var. zeae (based on a score of 1-5, 1 = resistant), grain yield/plant and 7 yield-related traits from a 2-year field evaluation of 126 collections of local varieties from the Punjab, 97 from...

Sukhova M.N., 1967: On the classification of the main fly species of the families muscidae calliphoridae sarcophagidae depending on the degree of their synanthropism and connections with domestic animals. Wiadomosci Botaniczne 13(4/5): 595-601

Herrod, H.G.; Warner, N.L., 1972: Inhibition by anti- chain sera of the cellular transfer of antibody and immunoglobulin synthesis in mice. Journal of Immunology 108(6): 1712-1717

Rufini, J.C.M.; Pio, R.; Ramos, J.D.; Gontijo, T.C.A.; Mendonca, V.; Coelho, J.H.C.; Alvares, B.F., 2002: Effect of sucrose and indolebutyric acid on the propagation of the sweet passion fruit by cuttings. Semi-hardwood cuttings (15 cm in length with 2 buds and one leaf cut at the middle) were obtained from one-year-old sweet passion fruit (Passiflora alata) vines in a commercial orchard in Itutinga, Minas Gerais, Brazil. The basal parts of the cutt...

Iupatov, S.I.; Smotrin, S.M., 1982: Treatment of post-thrombophlebitis and varicose ulcers of the lower extremities. Khirurgiia: 21-24

Fraser, W., 1985: The restoration/redevelopment and use of historic and old structures for commercial and non-commercial use. The paper suggests that tourism could act as a catalyst in the rebirth of lively downtown and harbourfront areas in the Eastern Caribbean. St. John's, in Antigua, is presented as a fairly typical example of a port and capital city once the ce...

Sijpesteijn, A.K., 1951: On Ruminococcus flavefaciens, a cellulose-decomposing bacterium from the rumen of sheep and cattle. Two strains of Ruminococcus flavefaciens, an important cellulose-decomposing bacterium, were isolated, one from the rumen of a sheep, the other from the rumen of a cow. Pure cultures were obtained by using the dilution method in agar media contain...