geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Interobserver agreement for the detection of Barrett's esophagus with optical frequency domain imaging


, : Interobserver agreement for the detection of Barrett's esophagus with optical frequency domain imaging. Digestive Diseases and Sciences 58(8): 2261-2265

Optical frequency domain imaging (OFDI) is a second-generation form of optical coherence tomography (OCT) providing comprehensive cross-sectional views of the distal esophagus at a resolution of ~7 ?m.Using validated OCT criteria for squamous mucosa, gastric cardia mucosa, and Barrett s esophagus (BE), the objective of this study was to determine the inter- and intra-observer agreements by a large number of OFDI readers for differentiating these tissues.OFDI images were obtained from nine subjects undergoing screening and surveillance for BE. Sixty-four OFDI image regions of interest were randomly selected for review. A training set of 19 images was compiled distinguishing squamous mucosa from gastric cardia and BE using previously validated OCT criteria. The ten readers then interpreted images in a test set of 45 different images of squamous mucosa (n = 15), gastric cardia (n = 15), or BE (n = 15). Interobserver agreement differentiating the three tissue types and BE versus non-BE mucosa was determined using multi-rater Fleiss s ? value. The images were later randomized again and four readers repeated the test 3 weeks later to assess intraobserver reliability.All ten readers showed excellent agreement for the differentiation of BE versus non-BE mucosa (? = 0.811 p < 0.0001) and for differentiating BE versus gastric cardia versus squamous mucosa (? = 0.866, p < 0.0001). For the four readers who repeated the test, the median intraobserver agreement (BE vs. non-BE) was high (? = 0.975, IQR: 0.94, 1.0).Trained readers have a high interobserver agreement for differentiating BE, squamous, and gastric cardia mucosa using OFDI.

US$19.90

PMID: 23508980

DOI: 10.1007/s10620-013-2625-x


Other references

Lutfi, E.; Riera-Heredia, Nàlia.; Córdoba, M.; Porte, C.; Gutiérrez, J.; Capilla, Eón.; Navarro, I., 2017: Tributyltin and triphenyltin exposure promotes in vitro adipogenic differentiation but alters the adipocyte phenotype in rainbow trout. Numerous environmental pollutants have been identified as potential obesogenic compounds affecting endocrine signaling and lipid homeostasis. Among them, well-known organotins such as tributyltin (TBT) and triphenyltin (TPT), can be found in signi...

Campana M.; Laborie C.; Barbier G.; Assan R.; Milcent R., 1991: Synthesis and cytotoxic activity on islets of langerhans of benzamide thiosemicarbazone derivatives. Eleven 1-(4-substituted .alpha.-arylaminobenzylidene)thiosemicarbazides 1 and the related semicarbazones 2 were synthesized and tested in vitro for their inhibitory effects on the islets of Langerhans. Only the thiosemicarbazones 1 suppressed the...

Williamson, E.H., 1985: Sagittal appliances for distalizing buccal segments in adults. Facial Orthopedics and Temporomandibular Arthrology 2(11): 4-7

Perry, R.D., 2015: Lydgate's <i>Danse Macabre</i> and the Trauma of the Hundred Years War. NlmCategory="UNASSIGNED">This essay argues that the foundational traumatic lacuna behind John Lydgate's Danse Macabre is the social agon between those who wage the Hundred Years War and those who fight in it. Drawing from the ins...

Benamer, H.; Aubry, P.; Himbert, D.; Boccara, A.; Juliard, J.M.; Boudvillain, O.; Steg, P.G., 1997: Increased cardiac troponin I is associated with complex coronary artery disease in unstable angina. European Heart Journal 18(ABSTR SUPPL ): 393

Castellanet, C., 1994: Is farming systems research and development (FSRD) a science? A review of the anglo-saxon literature. Farming systems research and development (FRSD) has been used and advocated by various researchers as an alternative to the traditional 'top-down' approach to agricultural research and development. However, its scientific status has freq...

Ogunba E.O., 1971: Studies on human filariasis in western nigeria. Journal of Parasitology 57(4 SECT 2 PART 1): 67

Wada, C., 2016: Practicing Siblings. Hawaii Dental Association Journal: 8-9

Lappi Blanco, E.; Soini, Y.; Paakko, P., 1999: Apoptotic activity is increased in the newly formed fibromyxoid connective tissue in bronchiolitis obliterans organizing pneumonia. Bronchiolitis obliterans organizing pneumonia (BOOP) and usual interstitial pneumonia (UIP) are clinically and histologically distinguishable interstitial lung diseases both sharing the presence of the newly formed fibromyxoid connective tissue as...

Bainton, D.; Davies, G.T.; Evans, K.T.; Gravelle, I.H., 1976: Gallbladder disease. Prevalence in a South Wales industrial town. In a weighted random sample of the specially enumerated population of a South Wales industrial town, examined by cholecystography for gallstones, the overall prevalence rates were 6.2 per cent for men 45 to 69 years of age and 12.1 per cent for wo...