+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Not smoking is associated with lower risk of hypertension: results of the Olivetti Heart Study

, : Not smoking is associated with lower risk of hypertension: results of the Olivetti Heart Study. European Journal of Public Health 24(2): 226-230

Few epidemiological investigations evaluated the role of smoking cessation on blood pressure (BP), and the results are not univocal. Therefore, the aim of this study was to assess the effect of smoking cessation on the risk to develop hypertension (HPT) and on BP values. This longitudinal study, with a follow-up period of 8 years, included the participants of the Olivetti Heart Study. Participants were 430 untreated normotensive non-diabetic men with normal renal function, examined twice in 1994–95 and in 2002–04. The sample included current smokers (S, n = 212), former smokers (ES, n = 145) and never smokers (NS, n = 73) at baseline. Basal body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were significantly higher in ES than in S (ES vs. S; BMI: 27.0 ± 2.5 vs. 26.1 ± 2.9 kg/m2; P < 0.01; SBP/DBP: 121.2 ± 9.3/80.0 ± 5.8 vs. 19.1 ± 9.9/77.4 ± 6.7 mm Hg; P < 0.05; M ± SD). After 8 years of follow-up, BP changes were significantly lower in ES than in S (SBP/DBP: 12.6 ± 13.4/7.9 ± 8.1 vs. 16.0 ± 14.9/10.3 ± 10.1 mm Hg; P < 0.05; M ± SD), also after adjustment for potential confounders. Moreover, at the last examination, the overall HPT prevalence was 33%, with lower values in ES than in S (25 vs. 38%, P = 0.01). After accounting for age, BP and BMI at baseline, and changes in smoking habit over the 8-year period, ES still had significant lower risk of HPT than S (odds ratio 0.30, 95% confidence interval 0.15–0.58; P < 0.01). In this sample of healthy men, smoking cessation was associated with lower BP increment and minor HPT risk, independently of potential confounders.


PMID: 23543678

DOI: 10.1093/eurpub/ckt041

Other references

Andales, A.; Green, T.; Ahuja, L.; Erskine, R.; Peterson, G., 2007: Temporally stable patterns in grain yield and soil water on a dryland catena. Grain yields from dryland cropping systems can be affected by water availability, topographic position, and crop rotation. The temporal stability over 14 years of observed spatial patterns is investigated by exploring: (1) relationships between gr...

Steinman, L., 2014: Pathogenic T helper 1 cells reach the brain before T helper 17 cells, and T regulatory cells suppress them albeit incompletely. Acta Neuropathologica 126(4): 517-518

Sando, William J., 1958: Lower Ordovician section near Chambersburg, Pennsylvania. The Beekmantown group, at least 3500 feet thick, is represented by Jie Stonehenge limestone and the Rockdale Run formation. Fossil identifications are recorded in measured sections, and the faunas are assigned in stratigraphic sequence to the Beli...

Grigor'eva, V.A.; Silikova, A.I., 1980: Valuable contribution to the biochemistry of muscles (A. I. Silikova). The paper deals with the results of scientific activity of A. I. Silakova (1908-1980) The main data are presented obtained by A. I. Silakova concerning the physiological role and transformation ways of glutamine in the muscular tissue. Her achieve...

Bird B.C.; Bedingfield G.; Gibson I.; Horne R.W., 1986: Stereomicroscopy of isolated r bodies from pseudomonas taeniospiralis and caedibacter taeniospiralis. Utilizing the facility of stereomicroscopy the R-body structures observed within various bacteria have been shown to be complex structures. They occasionally occur in intertwined pairs showing that a bacterium produces more than one R-body and the...

White, R.G.; Steel, J.W.; Leng, R.A.; Luick, J.R., 1969: Evaluation of 3 isotope dilution techniques for studying the kinetics of glucose metabolism in sheep. Biochemical Journal 114(2): 203-214

Anonymous, 2002: OPINION 2006 Cryphops Richter Richter, 1926 Conserved. Bulletin Of Zoological Nomenclature. 59(3): 206-208, 30 Ember

Lass, P.; Romanowicz, G.; Mizan, K.; Bandurski, T.; Afeltowicz, Z.; Lyczak, P., 2000: Tomographic cerebral blood flow scanning in diagnosis of psychiatric disorders. The paper summarises the role of tomographic cerebral blood flow SPECT scanning in psychiatric diagnostics, its' physical and radiopharmaceutical basis, pathological physiology of cerebrovascular circulation in psychiatric disorders and inter...

Eisenberg L., 1985: An examination of the t cell replacing factor assay reveals a heterogeneity of t cell replacing factor like activities. Supernatant fluid (SF) from the cloned M1sa.d-reactive helper T cell line L2V is a potent source of T cell replacing factor (TRF) activity. To determine whether L2V SF was representative of TRF-active supernatants, it was compared with supernatant...

Czekaj, J.; Dinh, Aélien.; Moldovan, A.; Vaudaux, P.; Gras, G.; Hoffmeyer, P.; Lew, D.; Bernard, L.; Uçkay, I., 2012: Efficacy of a combined oral clindamycin?rifampicin regimen for therapy of staphylococcal osteoarticular infections. A majority of osteoarticular and implant-related infections are due to staphylococci and biofilm formation. Combined therapy including rifampicin is frequently recommended. Indeed, rifampicin penetrates biofilms and kills adherent staphylococci, b...