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Relationship between impaired cardiac sympathetic activity and spatial dyssynchrony in patients with non-ischemic heart failure: assessment by MIBG scintigraphy and tagged MRI


, : Relationship between impaired cardiac sympathetic activity and spatial dyssynchrony in patients with non-ischemic heart failure: assessment by MIBG scintigraphy and tagged MRI. Journal of Nuclear Cardiology 20(4): 600-608

Impairment of cardiac sympathetic activity has various detrimental effects on cardiac function. The purpose was to investigate the relationship between left ventricular (LV) dyssynchrony and cardiac sympathetic activity in non-ischemic heart failure (HF).Twenty-seven patients with non-ischemic HF were enrolled. Cardiac sympathetic activity was assessed by heart-to-mediastinum ratio (H/M ratio) on 123I-Metaiodobenzylguanidine scintigraphy. LV dyssynchrony was assessed by cross-correlation analysis of time curves of myocardial circumferential strains delivered from cine-tagging MR images. Temporal dyssynchrony was defined as contraction delay between septal and lateral segments >110 milliseconds. Spatial dyssynchrony was defined as the negative value of the maximum correlation for the two strain time curves.H/M ratio was significantly lower for patients with spatial dyssynchrony compared to patients without (1.8 0.3 vs 2.1 0.3, P < .05). There was no difference between patients with and without temporal dyssynchrony (2.0 0.2 vs 2.0 0.3). The incidence of spatial dyssynchrony was significantly higher in patients with H/M ratio <2.0 than those whose ratios were ?2.0 (75% vs 20%, P = .001). There was no difference in the incidence of temporal dyssynchrony between the two groups (17% vs 20%).Impairment of cardiac sympathetic activity was found to be associated with spatial dyssynchrony in patients with non-ischemic HF.

US$19.90

PMID: 23653269

DOI: 10.1007/s12350-013-9715-1


Other references

Ren, Qingfeng., 1994: A study on quantity and ecology of Ardea cinerea and Nycticorax nycticorax in Ningxia. Ningxia Daxue Xuebao Ziran Kexue Ban. Jun; 152: 71-75 Sum No 46

Holloway, G., L.; Malcolm, J., R., 2007: Northern and southern flying squirrel use of space within home ranges in central Ontario. Partial harvesting can reduce the supply of dead and diseased trees in forests and as a result is predicted to negatively influence flying squirrel habitat. In this study, we measured the home range and habitat use of 13 radio-collared southern f...

Riksen, N.P.; Smits, P.; Rongen, G.A., 2006: The nonspecific anti-inflammatory therapy with methotrexate for patients with chronic heart failure. American Heart Journal 151(5): E5; Author Reply E6-7

Reszczyk, W.K.ossowski, W., 1975: The nutrition level of iron, boron, manganese and copper in the apple trees of three fruit-growing regions of Poland. Prace ub 1975), 17 81-100

Bednar, J.M.skova, I., 1977: Contribution to studies on the variability of micromorphological traits of genomes n, 2n, 3n, and 4n in Nicotiana tabacum L. Acta Sbornik Rada A: Spisy Fakulty agronomicke5(1): 35-40

Coey J.M.D., 1980: Clay minerals and their transformations studied with nuclear techniques; the contribution of Mossbauer spectroscopy. Atomic Energy Review = Revista de Energia Atomica = Revue d'Energie Atomique 18(1): 73-124

Kaya, S.; Weisner, D.; Schulz, R.; Semm, K., 1994: Prenatal diagnosis of severe stenosis of the ductus arteriosus Botalli in a twin pregnancy. Premature ductus arteriosus stenosis is a rare cardiovascular disease, which has a poor prognosis. The case presented was detected even in early pregnancy and was progressed rapidly to the stage of severe foetal heart failure. The patient was firs...

Babichev, S.I.; Filonov, A.V.; Iatsenko, A.A., 1984: Infection in inflammatory diseases of the biliary tract. Khirurgiia: 58-60

Bodansky, O.; Lewis, J.M.; Lillienfeld, M.C., 1943: The Concentration Of Vitamin A In The Blood Plasma During Pregnancy. Plasma vit. A and carotene detns. were carried out in 120 [female][female] at various stages of pregnancy; in 12 of them at some time during the first 2 trimesters and again in the 9th mo. In 70 cases, 6 mos. pregnant or less, the mean value of pl...

Lhoste, J., 1956: Sur un sousgenre nouveau de Scydmaenus Latreille, originaire de l'ile Maurice (Col. Scydmaenidae). Mauritius Institute Bulletin, 3: 283-286