geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Conservative management of thyroglobulin-positive, nonlocalizable thyroid carcinoma


, : Conservative management of thyroglobulin-positive, nonlocalizable thyroid carcinoma. Head & Neck 36(2): 155-157

The purpose of this study was to demonstrate a role for observation of patients with differentiated thyroid cancer (DTC) with persistent, nonlocalizable disease. Our study was conducted on outpatients seen at our institution from 1999 to 2009 having total thyroidectomy, radioactive iodine (RAI) ablation, measurable serum thyroglobulin (Tg), and no evidence of disease on whole body or positron emission tomography (PET) scans. Nineteen patients in our study group aged 20 to 73 with an average follow-up of 5.5 years (range, 2 12 years); all were treated with postoperative RAI (99 210 mCi, average 119). Mean Tg ranged from 0.41 to 4.34. Tg levels remained stable or gradually decreased in all patients. After total thyroidectomy and RAI therapy, patients may present with mildly elevated Tg values without localizable disease. These patients may have additional RAI treatments based on the Tg elevation. However, our clinical experience has shown that many of these patients will have Tg levels that either achieve stability or decrease over time without further treatment.

US$19.90

PMID: 23728951

DOI: 10.1002/hed.23272


Other references

D.G.acinto G.; Cantu R.; Ames A.; Dixon J., 1968: Hypotension a limiting factor in recovery from cerebral ischemia abstract rabbit epinephrine metab intra venous. Clinical Research 16(4): 512

Tsai, M-Hung.; Chen, Y-Chang.; Lien, J-Min.; Tian, Y-Chung.; Peng, Y-Shing.; Fang, J-Tseng.; Yang, C.; Tang, J-Hsiang.; Chu, Y-Yi.; Chen, P-Chi.; Wu, C-Shyong., 2008: Hemodynamics and metabolic studies on septic shock in patients with acute liver failure. Acute liver failure is often accompanied by hyperdynamic circulation, which is also a characteristic of septic shock. Pre-existing acute liver failure may worsen the hemodynamic impairment and prognosis in sepsis. To evaluate the hemodynamic and m...

Stadtman E.R.; Ginsburg A., 1974: The glutamine synthetase of escherichia coli structure and control. Boyer, Paul D (Ed ) The Enzymes, Vol 10 Protein Synthesis, Dna Synthesis And Repair, Rna Synthesis, Energy Linked Atpases, Synthetases 3rd Ed Xxviii+886p Illus Academic Press; New York, N Y , U S A ; London, England 755-807

Prosser, V.M.; Bailey, S.R., 2005: Bifurcating saphenous vein aorto-coronary bypass graft lesions: treatment of left main equivalent using two Filterwire EX distal protection devices. Distal protection devices for the prevention of embolization during saphenous venous aorto-coronary bypass graft intervention are currently considered standard of care. Branching or Y-type saphenous vein grafts present a unique and challenging pro...

Schröder, T.; Hering, J.P.; Hellige, G., 1995: Concomitant hemodynamic effects of intracoronary injections of a new transpulmonary contrast medium. A new transpulmonary echo contrast agent (SH U 508) was injected intracoronally to six anaesthetised sheep to examine its possible direct cardiac effects. SH U 508 was injected in randomised order in three different volumes (2, 4 and 8 ml; n = 12,...

Ruffing, M.; Heid, H.; Kleinschmidt, J.A., 1994: Mutations in the carboxy terminus of adeno-associated virus 2 capsid proteins affect viral infectivity: lack of an RGD integrin-binding motif. Using site-directed mutagenesis, we tested whether a potential integrin-binding site, (composed of the amino acids RGD) which is predicted in the adeno-associated virus 2 (AAV-2) capsid open reading frame (ORF), plays a role in the infectivity of...

Nakashima T.; Morita N.; Inoki M.; Nakanishi Y.; Tazumi T.; Kurogochi Y., 1980: Effects of hexose infusion with insulin and of additional epinephrine injection on the levels of serum potassium and blood glucose in dogs. The hypokalemic response was roughly proportional to the dose of insulin. The hypokalemia due to adding insulin to galactose or fructose loading was slightly greater than that with insulin and glucose or mannose loading, suggesting a hexose stereo...

Crema, A.; Milani, C.; Rovati, A.L., 1957: Pharmacology of Petasites officinalis & Petasites fragrans. Il Farmaco; Edizione Scientifica 12(9): 726-750

Demain, A.L., 1990: Achievements in microbial technology. In 1973, recombinant DNA technology was born and the age of the "new biotechnology" came upon us. Today we are seeing the amazing results of recombinant DNA technology, hybridoma technology, enzyme engineering and protein engineering. Th...

Traxler, M.J.; Fox, D.G.; Perry, T.C.; Dickerson, R.L.; Williams, D.L., 1995: Influence of roughage and grain processing in high-concentrate diets on the performance of long-fed Holstein steers. The effects of roughage source and timing of inclusion in high-concentrate diets on feedlot performance were evaluated in each of 2 yr with 144 and 120 long-fed Holstein steers, respectively. Roughage, when included in the diet, was delivered in a...