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Anatomical and procedural features associated with aortic root rupture during balloon-expandable transcatheter aortic valve replacement


, : Anatomical and procedural features associated with aortic root rupture during balloon-expandable transcatheter aortic valve replacement. Circulation 128(3): 244-253

Aortic root rupture is a major concern with balloon-expandable transcatheter aortic valve replacement (TAVR). We sought to identify predictors of aortic root rupture during balloon-expandable TAVR by using multidetector computed tomography.Methods and Results-Thirty-one consecutive patients who experienced left ventricular outflow tract (LVOT)/annular/aortic contained/noncontained rupture during TAVR were collected from 16 centers. A caliper-matched sample of 31 consecutive patients without annular rupture, who underwent pre-TAVR multidetector computed tomography served as a control group. Multidetector computed tomography assessment included short- and long-axis diameters and cross-sectional area of the sinotubular junction, annulus, and LVOT, and the presence, location, and extent of calcification of the LVOT, as well. There were no significant differences between the 2 groups in any preoperative clinical and echocardiographic variables. Aortic root rupture was identified in 20 patients and periaortic hematoma in 1Patients with root rupture had a higher degree of subannular/LVOT calcification quantified by the Agatston score (181.2±211.0 versus 22.5±37.6, P<0.001), and a higher frequency of ≥20% annular area oversizing (79.4% versus 29.0%, P<0.001) and balloon postdilatation (22.6% versus 0.0%, P=0.005). In conditional logistic regression analysis for the matched data, moderate/severe LVOT/subannular calcifications (odds ratio, 10.92; 95% confidence interval, 3.23–36.91; P<0.001) and prosthesis oversizing ≥20% (odds ratio, 8.38; 95% confidence interval, 2.67–26.33; P<0.001) were associated with aortic root contained/noncontained rupture.Conclusions-This study demonstrates that LVOT calcification and aggressive annular area oversizing are associated with an increased risk of aortic root rupture during TAVR with balloon-expandable prostheses. Larger studies are warranted to confirm these findings.

US$19.90

PMID: 23748467

DOI: 10.1161/CIRCULATIONAHA.113.002947


Other references

Yakovleva S.S., 1980: Use of calcium salts in the treatment of malignant tumors. Arkhiv Patologii 42(9): 93-94

Eliasof, S.; Jahr, C.E., 1997: Rapid AMPA receptor desensitization in catfish cone horizontal cells. AMPA and NMDA type glutamate receptors were studied in isolated catfish cone horizontal cells using the whole-cell and outside-out patch-recording techniques. In whole-cell recordings, cyclothiazide (CTZ) enhanced the peak current in response to g...

Kaiser, Jocelyn, 2003: Bush Pledges $15 Billion to Combat AIDS in 14 Countries. President Bush's pledge to increase U.S. spending on AIDS internationally has, in general, been welcomed by the public health community. On January 28, the president announced that the U.S. would channel $15 billion into AIDS treatment and pr...

Asada, L.N.; Sundefeld, G.C.; Alvarez, C.R.; Filho, S.Seckler.Ferreira.; Piveli, R.P., 2010: Water treatment plant sludge discharge to wastewater treatment works: effects on the operation of upflow anaerobic sludge blanket reactor and activated sludge systems. This experiment examined the effects of the discharge of water treatment plant (WTP) sludge into the following three types of wastewater treatment systems: a pilot-scale upflow anaerobic sludge blanket (UASB) reactor, a pilot-scale activated sludg...

Hindal, D.F., 1975: Additional studies on the relationship of cultural characteristics and pathogenicity in Ceratocystis ulmi. Isolates of C. ulmi (15 from N. America and 4 from Great Britain) were grown at 20 deg C for 6 days on 4 agar media: Difco potato dextrose agar (PDA); Difco malt extract agar (MEA); a glucose/yeast extract agar (GYE); and a defined glucose/L-aspar...

Anonymous, 2002: World trade 2000: a year of strong growth. In 2000 the volume of world commodities exports grew by 12.0%, including 8.0% growth in trade in agricultural commodities. World production of commodities grew by 4.5% in 2000, and world production of agricultural commodities by 1.0%. The total va...

Rizou, G.; Mamzoridi, K.; Kostopoulou, E.; Siupotina, M.; Haidas, S.; Makrigiannis, K., 1997: Consumption of antibiotics under restriction, in Larisa Hospital, Greece. European Journal of Clinical Pharmacology 52(SUPPL ): A183

Lohumi, S.; Joshi, R.; Kandpal, L.Mohan.; Lee, H.; Kim, M.S.; Cho, H.; Mo, C.; Seo, Y-Wook.; Rahman, A.; Cho, B-Kwan., 2017: Quantitative analysis of Sudan dye adulteration in paprika powder using FTIR spectroscopy. As adulteration of foodstuffs with Sudan dye, especially paprika- and chilli-containing products, has been reported with some frequency, this issue has become one focal point for addressing food safety. FTIR spectroscopy has been used extensively...

Chervyakova K.I.; Persianova I.P.; Makarchuk F.T., 1972: Use of fluorescent antibodies to detect thermophilic bacteria during manufacture of canned foods. Prikladnaya Biokhimiya i Mikrobiologiya 8(4): 495-497

Yasuda K.; Shibata K.; Honma S.; Seki T.; Hasumi K.; Masuda T.; Izumi A.; Ishimori T.; Gotanda K.; Uno M., 1989: Antihypertensive pyridazinone aminoisopropanol derivatives us patent 4843072 june 27 1989. Official Gazette of the United States Patent & Trademark Office Patents 1103(4): 2560