geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Antiluteolytic effect of the embryo


, : Antiluteolytic effect of the embryo. Ciba Foundation Symposium: 261-292

In several mammalian species, prostaglandin F2 alpha (PGF2 alpha) released from the uterus causes corpus luteum regression, and thereby regulates the length of the oestrous cycle or pseudopregnancy. If the animal becomes pregnant, luteal regression must be prevented since ovarian progesterone is necessary for pregnancy maintenance during at least the first one-third of pregnancy. Evidence is presented that the guinea-pig conceptus produces an antiluteolytic factor which suppresses PGF2 alpha output from the uterus by preventing the increase in uterine PGF2 alpha-synthesizing capacity which occurs around the time of luteolysis. Experiments in unilaterally pregnant guinea-pigs, with either an intact or a transected sterile horn, indicate that this factor acts both locally systemically, though separation of the two uterine horns does greatly reduce its effect on the sterile side. Oestradiol administered during early pregnancy induces abortion, which is associated with a high PGF2 alpha-synthesizing capacity of the uterus. However, luteal regression does not take place while the conceptuses are in the uterus. Spontaneously aborting guinea-pigs behave similarly. The conceptus may therefore secrete a luteotrophic hormone as well. Luteal maintenance during early pregnancy in other species is discussed, since experiments on sheep indicate that the sheep embryo may also secrete an antiluteolytic factor.

US$29.90

PMID: 259041


Other references

Voskuil, M.,.; Kroft, L.J.M.; Hazekamp, M.G.; Lubbers, W.J.; Ottenkamp, J.; Wall, E.E.; Mulder, B.J.M., 1997: Natural history and postsurgical follow-up in patients with congenitally corrected transposition of the great arteries. Circulation 96(8 SUPPL ): I98, 10/21/97

Shulman, S.; Mayes, L.C.; Cohen, T.H.; Swain, J.E.; Leckman, J.F., 2008: Romantic attraction and conflict negotiation among late adolescent and early adult romantic couples. In a sample of 35 couples (college students, aged 18-24) who were dating for no longer than six months, each partner was given a semi-structured interview to assess the nature and intensity of romantic preoccupation with his or her lover. In addit...

Lederhouse, RC., 1982: Factors affecting equal catchability in two swallowtail butterflies, Papilio polyxenes and P. glaucus. Recapture probabilities were analysed for individually marked Papilio polyxenes F. and P. glaucus L. in the USA. Recapture rates differed with sex and behaviour at time of capture for P. polyxenes, but not with age. For P. glaucus, only difference...

Gardner James S., 1995: Monitoring glacier fluctuations in the context of climatic change, western Himalaya. Pages 97-105 1995

Infante, M., 2015: A conservative approach for subsolid lung nodules: is it safe enough?. European Respiratory Journal 45(3): 592-595

Brink P.R.; Ramanan S.V., 1985: A model for the diffusion of fluorescent probes in the septate giant axon of earthworm lumbricus axoplasmic diffusion and junctional membrane permeability. The diffusion of the 3 fluorescent probes dichlorofluorescein, carboxyfluorescein, and Lucifer Yellow within the septate median giant axon of the earthworm was monitored using fluorometric methods. A diffusion model was derived that allowed comput...

Tsui, E.; Au, S.Y.; Wong, C.P.; Cheung, A.; Lam, P., 2015: Development of an automated model to predict the risk of elderly emergency medical admissions within a month following an index hospital visit: a Hong Kong experience. To develop an automated risk prediction model to identify elderly patients at high risk of emergency admission to medical wards within 28 days following an index hospital visit. A retrospective data analysis of 41 hospitals and 48 specialist outpa...

Song, K.Yong., 2013: High-sensitivity optical time-domain reflectometry based on Brillouin dynamic gratings in polarization maintaining fibers. A high-sensitivity optical time-domain reflectometry based on Brillouin dynamic grating (BDG) is proposed and experimentally demonstrated in polarization-maintaining fibers, where a single-end access to a fiber under test is applied with co-propag...

Sanchez Marco, A., 1999: Palaeornithological catalogue for the Iberian and Balearic Tertiary Catalogo paleornitologico del Terciario Iberico y Balear. It is reported sixty three tertiary localities having avian remains accounting those situated both in the Iberian peninsula and in the Balearic islands. Approximately, ten of these sites yield individual species or collections of most interest. A...

Zagol, B.; Book, S.; Krasuski, R.A., 2006: Late "adult form" scimitar syndrome presenting with "infant form" complications. This case report describes an 85-year-old woman with complications resulting from scimitar syndrome, anomalous drainage of the right pulmonary veins into the inferior vena cava. In addition to being the oldest reported case of this congenital anom...